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Proteolysis

Fulvestrant-Induced Cell Death and Proteasomal Degradation of Estrogen Receptor α Protein in MCF-7 Cells Require the CSK c-Src Tyrosine Kinase

Wei-Lan Yeh, Keiko Shioda, Kathryn R. Coser, Danielle Rivizzigno, Kristen R. McSweeney, Toshi Shioda

published 04 Apr 2013

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A Systematic In Silico Search for Target Similarity Identifies Several Approved Drugs with Potential Activity against the Plasmodium falciparum Apicoplast

Nadlla Alves Bispo, Richard Culleton, Lourival Almeida Silva, Pedro Cravo

published 26 Mar 2013

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PPARβ/δ Regulates Glucocorticoid- and Sepsis-Induced FOXO1 Activation and Muscle Wasting

Estibaliz Castillero, Nima Alamdari, Zaira Aversa, Aniket Gurav, Per-Olof Hasselgren

published 21 Mar 2013

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Leucine and Protein Metabolism in Obese Zucker Rats

Pengxiang She, Kristine C. Olson, Yoshihiro Kadota, Ayami Inukai, Yoshiharu Shimomura, Charles L. Hoppel, Sean H. Adams, Yasuko Kawamata, Hideki Matsumoto, Ryosei Sakai, Charles H. Lang, Christopher J. Lynch

published 20 Mar 2013

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RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells

Caihong Yang, Kristen L. Shogren, Ribu Goyal, Dalibel Bravo, Michael J. Yaszemski, Avudaiappan Maran

published 19 Mar 2013

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Proteasome-Mediated Proteolysis of SRSF5 Splicing Factor Intriguingly Co-occurs with SRSF5 mRNA Upregulation during Late Erythroid Differentiation

Osman Breig, Faouzi Baklouti

published 11 Mar 2013

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Cellular Catabolism of the Iron-Regulatory Peptide Hormone Hepcidin

Gloria Cuevas Preza, Rogelio Pinon, Tomas Ganz, Elizabeta Nemeth

published 11 Mar 2013

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Non-Specific Protein Modifications by a Phytochemical Induce Heat Shock Response for Self-Defense

Kohta Ohnishi, Shinya Ohkura, Erina Nakahata, Akari Ishisaka, Yoshichika Kawai, Junji Terao, Taiki Mori, Takeshi Ishii, Tsutomu Nakayama, Noriyuki Kioka, Shinya Matsumoto, Yasutaka Ikeda, Minoru Akiyama, Kazuhiro Irie, Akira Murakami

published 11 Mar 2013

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Altered Processing of Amyloid Precursor Protein in Cells Undergoing Apoptosis

Tina Fiorelli, Lisa Kirouac, Jaya Padmanabhan

published 28 Feb 2013

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Molecular Basis of Differential Sensitivity of Myeloma Cells to Clinically Relevant Bolus Treatment with Bortezomib

Tamer B. Shabaneh, Sondra L. Downey, Ayrton L. Goddard, Michael Screen, Marcella M. Lucas, Alan Eastman, Alexei F. Kisselev

published 27 Feb 2013

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Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells

Barbara Del Bello, Marzia Toscano, Daniele Moretti, Emilia Maellaro

published 20 Feb 2013

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Myotonia Congenita Mutation Enhances the Degradation of Human CLC-1 Chloride Channels

Ting-Ting Lee, Xiao-Dong Zhang, Chao-Chin Chuang, Jing-Jer Chen, Yi-An Chen, Shu-Ching Chen, Tsung-Yu Chen, Chih-Yung Tang

published 12 Feb 2013

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Alterations in ROS Activity and Lysosomal pH Account for Distinct Patterns of Macroautophagy in LINCL and JNCL Fibroblasts

José Manuel Vidal-Donet, Jaime Cárcel-Trullols, Bonaventura Casanova, Carmen Aguado, Erwin Knecht

published 07 Feb 2013

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