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Proteases

X-ray crystallographic and hydrogen deuterium exchange studies confirm alternate kinetic models for homolog insulin monomers

Esra Ayan, Miray Türk, Özge Tatlı, Sevginur Bostan, Elek Telek, Baran Dingiloğlu, B. Züleyha Doğan, Muhammed Ikbal Alp, Ahmet Katı, Gizem Dinler-Doğanay, Hasan Demirci

published 21 Apr 2025

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An SDS-NaOH-based method to isolate genome of recombinant adeno-associated virus vectors for physical titer measurement

Xiangying Zhu, Keying Yang, Jinyan Xie, Xilin Feng, Tao Wu, Mengjun Hu, Haijian Wang, Chenghui Yu, Xiaomin Yu, Farhid Hemmatzadeh, Liqing Zhu, Linhua Zhang

published 03 Apr 2025

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Integration of metabolomics and chemometrics with in-silico and in-vitro approaches to unravel SARS-Cov-2 inhibitors from South African plants

Karabo Maselepe Makoana, Clarissa Marcelle Naidoo, Muhammad Sulaiman Zubair, Mmei Cheryl Motshudi, Nqobile Monate Mkolo

published 26 Mar 2025

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Identification of cross-reactive vaccine antigen candidates in Gram-positive ESKAPE pathogens through subtractive proteome analysis using opsonic sera

Océane Sadones, Eliza Kramarska, Maite Sainz-Mejías, Rita Berisio, Johannes Huebner, Siobhán McClean, Felipe Romero-Saavedra

published 26 Mar 2025

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Microfluidic isolation and release of live disseminated breast tumor cells in bone marrow

Minh-Chau N. Le, Dongjiang Chen, Kierstin A. Smith, David D. Tran, Z. Hugh Fan

published 12 Mar 2025

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Analysis of differential expression of matrix metalloproteinases and defensins in the nasopharyngeal milieu of mild and severe COVID-19 cases

Khekashan Imtiaz, Nida Farooqui, Khalid Ahmed, Alnara Zhamalbekova, Muhammad Faraz Anwar, Asghar Nasir, Zeeshan Ansar, Khitab Gul, Azhar Hussain, Antonio Sarría-Santamera, Syed Hani Abidi

published 18 Feb 2025

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Extraction of coronary thrombus-derived exosomes from patients with acute myocardial infarction and its effect on the function of adventitial cells

Youfu He, Bo Wang, Yu Qian, Debin Liu, Qiang Wu

published 16 Jan 2025

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N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade

Nina Germitsch, Tobias Kockmann, Manuela Schnyder, Lucienne Tritten

published 15 Jan 2025

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Sequence and biochemical analysis of vaccinia virus A32 protein: Implications for in vitro stability and coiled-coil motif mediated regulation of the DNA-dependent ATPase activity

Uma Ramakrishnan, Tanvi Aggarwal, Kiran Kondabagil

published 06 Jan 2025

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Clade-1 Vap virulence proteins of Rhodococcus equi are associated with the cell surface and support intracellular growth in macrophages

Zeynep Yerlikaya, Raúl Miranda-CasoLuengo, Yuting Yin, Cheng Cheng, Wim G. Meijer

published 06 Jan 2025

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Performance and quality of eggs of laying hens fed with Moringa Oleifera leaf flour

Rogério Ventura da Silva Junior, Carlos Bôa-Viagem Rabello, Maria do Carmo Mohaupt Marques Ludke, Cláudia da Costa Lopes, Waleska Rocha Leite de Medeiros Ventura, Elayne de Souza Rocha Soares, Patricia Maria Guedes Paiva, Thiago Henrique Napoleão, Apolonio Gomes Ribeiro, Júlio Cézar dos Santos Nascimento, Lilian Francisco Arantes de Souza, Helia Sharlane de Holanda Oliveira

published 31 Dec 2024

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Profiling endogenous airway proteases and antiproteases and modeling proteolytic activation of Influenza HA using in vitro and ex vivo human airway surface liquid samples

Stephanie A. Brocke, Boris Reidel, Camille Ehre, Meghan E. Rebuli, Carole Robinette, Kevin D. Schichlein, Christian A. Brooks, Ilona Jaspers

published 31 Dec 2024

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A cell-based Papain-like Protease (PLpro) activity assay for rapid detection of active SARS-CoV-2 infections and antivirals

Anahi G. Jimenez-Campos, Lucas I. Maestas, Nileena Velappan, Brian Beck, Chunyan Ye, Keith Wernsing, Yaniksa Mata-Solis, William J. Bruno, Silas C. Bussmann, Steven Bradfute, Justin T. Baca, Frauke H. Rininsland

published 26 Dec 2024

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