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Proteases

Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Cheila Rocha, Prerna Arora, Lu Zhang, Anzhalika Sidarovich, Luise Graichen, Anna-Sophie Moldenhauer, Stefan Pöhlmann, Markus Hoffmann

published 14 Aug 2025

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Platelet count and coagulation profiles of adult hypertensive patients at Felege Hiwot comprehensive specialized hospital, Northwest Ethiopia: A comparative cross-sectional study

Mitku Kassa, Yemataw Gelaw, Mesay Arkew, Haftu Asmerom, Kabtamu Gemechu, Elias Shiferaw

published 12 Aug 2025

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Interactions of substrates and phosphinyl containing inhibitors with bacterial and human zinc proteases

Fatema Amatur Rahman, Imin Wushur, Ida Kristine Østnes Hansen, Tor Haug, Klara Stensvåg, Bibek Chaulagain, Tra-Mi Nguyen, Olayiwola Adedotun Adekoya, Nabin Malla, Jan-Olof Winberg, Ingebrigt Sylte

published 01 Aug 2025

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Blood pressure variability combined with coagulation function in early prediction and outcome assessment of germinal matrix-intraventricular hemorrhage in preterm infants with gestational age ≤32 weeks

Lijun Jiang, Qian Yu, Hui Li, Fudong Wang, Feng Liu, Zhenxing Xu

published 24 Jul 2025

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Calcium-dependent pathway as a primary cause of hypoxic RGC damage in monkey retinal explants

Emi Nakajima, Momoko Otsugu-Kobayashi, Takatoshi Uchida, Kana Orihara, Thomas R. Shearer, Mitsuyoshi Azuma

published 11 Jul 2025

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pET28g: A Golden Gate-compatible pET vector for protein expression in Escherichia coli, validated by production of functional human ACE2

Inês M. Luís, Mariana Parada, João B. Vicente, Isabel A. Abreu

published 07 Jul 2025

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Loss of a major venom toxin gene in a Western Diamondback rattlesnake population

Noah L. Dowell, Elizabeth Cahill, Sean B. Carroll

published 03 Jul 2025

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Insecticidal potential of five medicinal plants: An In Vitro evaluation and molecular docking analysis of Artemisia absinthium

Mohd Yaseen, Mudasir Gani, Shabir Ahmad Ganai, Baseerat ul Ann, Fehim Jeelani Wani, Mohd Ayoub Mantoo, Khalid Rasool, Rashid Mumtaz Khan

published 01 Jul 2025

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The influence of proteolytic enzymes on the change of lysozyme properties

Łukasz Tomczyk, Grzegorz Leśnierowski, Aneta Tomczak, Jubilee Amajuoritse Ajemigbitse, Tomasz Szablewski, Renata Cegielska-Radziejewska

published 26 Jun 2025

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In-silico study of approved drugs as potential inhibitors against 3CLpro and other viral proteins of CoVID-19

Imra Aqeel, Abdul Majid, Tahani Jaser Alahmadi, Areej Althubaity

published 25 Jun 2025

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Computer-aided discovery of dual-target compounds for Alzheimer’s from ayurvedic medicinal plants

Mohibullah Shah, Sadia Pervaiz, Iqra Ahmad, Shahid Habib Ansari, Valdir Ferreira De Paula Junior, Sibtain Ahmed, Muhammed Umer Khan, Khaled Fahmi Fawy, Umar Nishan, Hanna Dib, Mohamed A.O. Abdelfattah

published 25 Jun 2025

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Protein landscape of the brush border membrane of first instar larvae of Frankliniella occidentalis, the western flower thrips

Marlonni Maurastoni, Dorith Rotenberg, Ruchir Mishra, Bryony C. Bonning, Anna E. Whitfield

published 24 Jun 2025

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The relationship between pollen monodiets and the activities of proteolytic systems in the fat body and hemolymph of honeybee workers

Maciej Sylwester Bryś, Krzysztof Olszewski, Aneta Strachecka

published 18 Jun 2025

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