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Proteases

Discovery of novel West Nile Virus protease inhibitor based on isobenzonafuranone and triazolic derivatives of eugenol and indan-1,3-dione scaffolds

André S. de Oliveira, Poliana A. R. Gazolla, Ana Flávia C. da S. Oliveira, Wagner L. Pereira, Lívia C. de S. Viol, Angélica F. da S. Maia, Edjon G. Santos, Ítalo E. P. da Silva, Tiago A. de Oliveira Mendes, Adalberto M. da Silva, Roberto S. Dias, Cynthia C. da Silva, Marcelo D. Polêto, Róbson R. Teixeira, Sergio O. de Paula

published 26 Sep 2019

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Exploration of icariin analog structure space reveals key features driving potent inhibition of human phosphodiesterase-5

Yasmin Chau, Fu-Shuang Li, Olesya Levsh, Jing-Ke Weng

published 20 Sep 2019

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Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up

Clemens Grupp, Ilka Troche-Polzien, Johanna Stock, Carsten Bramlage, Gerhard A. Müller, Michael Koziolek

published 20 Sep 2019

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Comparative compositional and functional analyses of Bothrops moojeni specimens reveal several individual variations

Weslei da Silva Aguiar, Nathália da Costa Galizio, Caroline Serino-Silva, Sávio Stefanini Sant’Anna, Kathleen Fernandes Grego, Alexandre Keiji Tashima, Erika Sayuri Nishiduka, Karen de Morais-Zani, Anita Mitico Tanaka-Azevedo

published 12 Sep 2019

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EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation

Mei-Ling Li, Jing-Yi Lin, Bo-Shiun Chen, Kuo-Feng Weng, Shin-Ru Shih, Jesse Davila Calderon, Blanton S. Tolbert, Gary Brewer

published 09 Sep 2019

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Neural computational model GrowthEstimate: A model for studying living resources through digestive efficiency

Krisna Rungruangsak-Torrissen, Poramate Manoonpong

published 28 Aug 2019

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The association of high-normal international-normalized-ratio (INR) with mortality in patients referred for coronary angiography

Graciela E. Delgado, Andreas Zirlik, Rudolf Gruber, Thomas Scheffold, Bernhard K. Krämer, Winfried März, Marcus E. Kleber

published 15 Aug 2019

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A novel and highly efficient purification procedure for native human dipeptidyl peptidase 3 from human blood cell lysate

Paul Kaufmann, Matthias Muenzner, Mandy Kästorf, Karine Santos, Tobias Hartmann, Anke Dienelt, Linda Rehfeld, Andreas Bergmann

published 07 Aug 2019

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NHBA is processed by kallikrein from human saliva

Elisa Pantano, Sara Marchi, Massimiliano Biagini, Martina Di Fede, Vincenzo Nardi Dei, Silvia Rossi Paccani, Mariagrazia Pizza, Elena Cartocci

published 01 Aug 2019

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Evaluation of the sensitivity and specificity of a novel line immunoassay for the detection of criteria and non-criteria antiphospholipid antibodies in comparison to established ELISAs

Markus A. Thaler, Andreas Bietenbeck, Udo Steigerwald, Thomas Büttner, Peter Schierack, Edelgard Lindhoff-Last, Dirk Roggenbuck, Peter B. Luppa

published 24 Jul 2019

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Tissue specific alpha-2-Macroglobulin (A2M) splice isoform diversity in Hilsa shad, Tenualosa ilisha (Hamilton, 1822)

Vindhya Mohindra, Tanushree Dangi, Labrechai Mog Chowdhury, J. K. Jena

published 23 Jul 2019

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Increased expression of blood muscarinic receptors in patients with reflex syncope

Maxime Beutelstetter, Angelo Livolsi, Hugues Greney, Pauline Helms, Catherine Schmidt-Mutter, Charlie De Melo, Gerald Roul, Florian Zores, Alexandre Bolle, Nassim Dali-Youcef, Magali Beaugey, Alban Simon, Nathalie Niederhoffer, Jacques Regnard, Malika Bouhaddi, Chris Adamopoulos, Mickael Schaeffer, Erik Sauleau, Pascal Bousquet

published 18 Jul 2019

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Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

Anne Ward, Jason R. Hollister, Young Pyo Choi, Brent Race, Katie Williams, Daniel W. Shoup, Roger A. Moore, Suzette A. Priola

published 10 Jul 2019

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