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Proteases

Exposure to mold proteases stimulates mucin production in airway epithelial cells through Ras/Raf1/ERK signal pathway

Xianxian Wu, Boram Lee, Lingxiang Zhu, Zhi Ding, Yin Chen

published 22 Apr 2020

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Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2)

Gwendolyn Vliegen, Kaat Kehoe, An Bracke, Emilie De Hert, Robert Verkerk, Erik Fransen, Bart ‘s Jongers, Esther Peters, Anne-Marie Lambeir, Samir Kumar-Singh, Peter Pickkers, Philippe G. Jorens, Ingrid De Meester

published 21 Apr 2020

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Repurposing anti-diabetic drug “Sitagliptin” as a novel virulence attenuating agent in Serratia marcescens

Hisham A. Abbas, Wael A. H. Hegazy

published 16 Apr 2020

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Pre-existing resistance associated polymorphisms to NS3 protease inhibitors in treatment naïve HCV positive Pakistani patients

Hafeez Ullah Khan, Sanaullah Khan, Muhammad Akbar Shah, Sobia Attaullah, Muhammad Arshad Malik

published 10 Apr 2020

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Polymorphisms and drug resistance analysis of HIV-1 isolates from patients on first line antiretroviral therapy (ART) in South-eastern Nigeria

Augustine O. Udeze, David O. Olaleye, Georgina N. Odaibo

published 08 Apr 2020

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Characterisation of ACP5 missense mutations encoding tartrate-resistant acid phosphatase associated with spondyloenchondrodysplasia

Janani Ramesh, Latha K. Parthasarathy, Anthony J. Janckila, Farhana Begum, Ramya Murugan, Balakumar P. S. S. Murthy, Rif S. El-Mallakh, Ranga N. Parthasarathy, Bhuvarahamurthy Venugopal

published 26 Mar 2020

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Three-dimensional brain-on-chip model using human iPSC-derived GABAergic neurons and astrocytes: Butyrylcholinesterase post-treatment for acute malathion exposure

Lumei Liu, Youngmi Koo, Teal Russell, Elaine Gay, Yan Li, Yeoheung Yun

published 12 Mar 2020

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Extracellular vesicles from rat-bone-marrow mesenchymal stromal/stem cells improve tendon repair in rat Achilles tendon injury model in dose-dependent manner: A pilot study

Clarissa Gissi, Annalisa Radeghieri, Cristina Antonetti Lamorgese Passeri, Marialucia Gallorini, Lucia Calciano, Francesco Oliva, Francesca Veronesi, Andrea Zendrini, Amelia Cataldi, Paolo Bergese, Nicola Maffulli, Anna Concetta Berardi

published 12 Mar 2020

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Interactive molecular dynamics in virtual reality for accurate flexible protein-ligand docking

Helen M. Deeks, Rebecca K. Walters, Stephanie R. Hare, Michael B. O’Connor, Adrian J. Mulholland, David R. Glowacki

published 11 Mar 2020

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Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica

Brenda H. Welter, Heather A. Walters, Lesly A. Temesvari

published 05 Mar 2020

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Maintenance of spontaneous breathing at an intensity of 60%–80% may effectively prevent mechanical ventilation-induced diaphragmatic dysfunction

Zujin Luo, Silu Han, Wei Sun, Yan Wang, Sijie Liu, Liu Yang, Baosen Pang, Jiawei Jin, Hong Chen, Zhixin Cao, Yingmin Ma

published 04 Mar 2020

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Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin

Winnie Tan, Vincent J. Murphy, Aude Charron, Sylvie van Twest, Michael Sharp, Angelos Constantinou, Michael W. Parker, Wayne Crismani, Rohan Bythell-Douglas, Andrew J. Deans

published 24 Feb 2020

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The PAR2 signal peptide prevents premature receptor cleavage and activation

Belinda Liu, Grace Lee, Jiejun Wu, Janise Deming, Chester Kuei, Anthony Harrington, Lien Wang, Jennifer Towne, Timothy Lovenberg, Changlu Liu, Siquan Sun

published 20 Feb 2020

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