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Proteases

All-age whole mount in situ hybridization to reveal larval and juvenile expression patterns in zebrafish

Franz Vauti, Luisa A. Stegemann, Viktoria Vögele, Reinhard W. Köster

published 07 Aug 2020

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Papain-cetylpyridinium chloride and pepsin-cetylpyridinium chloride; two novel, highly sensitive, concentration, digestion and decontamination techniques for culturing mycobacteria from clinically suspected pulmonary tuberculosis cases

Pottathil Shinu, Varsha A. Singh, Anroop Nair, Katharigatta N. Venugopala, Sabah H. Akrawi

published 04 Aug 2020

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A mathematical model to quantify the effects of platelet count, shear rate, and injury size on the initiation of blood coagulation under venous flow conditions

Anass Bouchnita, Kirill Terekhov, Patrice Nony, Yuri Vassilevski, Vitaly Volpert

published 29 Jul 2020

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Nonspecific cleavages arising from reconstitution of trypsin under mildly acidic conditions

Ben Niu, Michael Martinelli II, Yang Jiao, Chunlei Wang, Mingyan Cao, Jihong Wang, Eric Meinke

published 28 Jul 2020

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Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins

Naoki Tanaka, Michiaki Okuda, Tatsutoshi Nishigaki, Nobuhiko Tsuchiya, Yukako Kobayashi, Takuya Uemura, Sayaka Kumo, Hachiro Sugimoto, Seiji Miyata, Tomonori Waku

published 24 Jul 2020

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In silico identification of potential inhibitors of key SARS-CoV-2 3CL hydrolase (Mpro) via molecular docking, MMGBSA predictive binding energy calculations, and molecular dynamics simulation

M. Iqbal Choudhary, Muniza Shaikh, Atia- tul-Wahab, Atta- ur-Rahman

published 24 Jul 2020

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OCIAD1 is a host mitochondrial substrate of the hepatitis C virus NS3-4A protease

Huong T. L. Tran, Kenichi Morikawa, Anggakusuma, Rose Zibi, Viet Loan Dao Thi, François Penin, Markus H. Heim, Manfredo Quadroni, Thomas Pietschmann, Jérôme Gouttenoire, Darius Moradpour

published 22 Jul 2020

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Inhibitors of metalloprotease, γ-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication

Alice Liu, Cristhian J. Ildefonso, Wesley S. Bond, Mary Y. Hurwitz, Richard L. Hurwitz

published 22 Jul 2020

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Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study

Huiyu Zhou, Mei Zhu, Ling Ma, Jinming Zhou, Biao Dong, Guoning Zhang, Shan Cen, Yucheng Wang, Juxian Wang

published 22 Jul 2020

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The interaction between cuticle free fatty acids (FFAs) of the cockroaches Blattella germanica and Blatta orientalis and hydrolases produced by the entomopathogenic fungus Conidiobolus coronatus

Agata Kaczmarek, Mieczysława Irena Boguś, Emilia Włóka, Anna Katarzyna Wrońska, Anna Krawiel, Michalina Kazek, Katarzyna Zalewska, Katarzyna Kłocińska-Biały, Martyna Sobocińska, Aleksandra Gliniewicz, Ewa Mikulak, Marta Matławska

published 09 Jul 2020

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Visualisation tools for dependent peptide searches to support the exploration of in vitro protein modifications

George W. Preston, Liping Yang, David H. Phillips, Claudia S. Maier

published 08 Jul 2020

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Combinatorial effects of antibiotics and enzymes against dual-species Staphylococcus aureus and Pseudomonas aeruginosa biofilms in the wound-like medium

Rima Fanaei Pirlar, Mohammad Emaneini, Reza Beigverdi, Maryam Banar, Willem B. van Leeuwen, Fereshteh Jabalameli

published 25 Jun 2020

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Structural and biochemical characterization of a novel thermophilic Coh01147 protease

Hossein Tarrahimofrad, Amir Meimandipour, Sareh Arjmand, Mohammadtaghi Beigi Nassiri, Ehsan Jahangirian, Hossein Tavana, Javad Zamani, Somayyeh Rahimnahal, Saeed Aminzadeh

published 23 Jun 2020

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