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Proteases

Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library

Hidenori Yano, Daisuke Nishimiya, Yoshirou Kawaguchi, Masakazu Tamura, Ryuji Hashimoto

published 29 Dec 2020

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C-reactive protein can predict dose intensity, time to treatment failure and overall survival in HCC treated with lenvatinib

Tsuguru Hayashi, Michihiko Shibata, Shinji Oe, Koichiro Miyagawa, Yuichi Honma, Masaru Harada

published 22 Dec 2020

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Female reproductive tract has low concentration of SARS-CoV2 receptors

Jyoti Goad, Joshua Rudolph, Aleksandar Rajkovic

published 14 Dec 2020

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Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24

Kaitlin M. Wood, Eric D. Spear, Otto W. Mossberg, Kamsi O. Odinammadu, Wenxin Xu, Susan Michaelis

published 14 Dec 2020

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In-depth characterization and comparison of the N-glycosylated proteome of two-dimensional- and three-dimensional-cultured breast cancer cells and xenografted tumors

Yonghong Mao, Yang Zhao, Yong Zhang, Hao Yang

published 10 Dec 2020

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Assessment of Vibrio parahaemolyticus levels in oysters (Crassostrea virginica) and seawater in Delaware Bay in relation to environmental conditions and the prevalence of molecular markers to identify pathogenic Vibrio parahaemolyticus strains

Esam Almuhaideb, Lathadevi K. Chintapenta, Amanda Abbott, Salina Parveen, Gulnihal Ozbay

published 03 Dec 2020

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Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans

Ayaka Imanishi, Yuma Aoki, Masaki Kakehi, Shunsuke Mori, Tomomi Takano, Yukihiko Kubota, Hon-Song Kim, Yukimasa Shibata, Kiyoji Nishiwaki

published 02 Dec 2020

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Repurposing therapeutics for COVID-19: Rapid prediction of commercially available drugs through machine learning and docking

Sovesh Mohapatra, Prathul Nath, Manisha Chatterjee, Neeladrisingha Das, Deepjyoti Kalita, Partha Roy, Soumitra Satapathi

published 12 Nov 2020

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High CSF thrombin concentration and activity is associated with an unfavorable outcome in patients with intracerebral hemorrhage

Harald Krenzlin, Christina Frenz, Jan Schmitt, Julia Masomi-Bornwasser, Dominik Wesp, Darius Kalasauskas, Thomas Kerz, Johannes Lotz, Beat Alessandri, Florian Ringel, Naureen Keric

published 11 Nov 2020

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Analysis of RNA yield in extracellular vesicles isolated by membrane affinity column and differential ultracentrifugation

Gilberto Gutiérrez García, Gabriela Galicia García, Jessica Zalapa Soto, Andrea Izquierdo Medina, Mariana Rotzinger-Rodríguez, Gustavo Antonio Casas Aguilar, Cynthia Paola López Pacheco, Álvaro Aguayo, Maria Montserrat Aguilar-Hernandez

published 06 Nov 2020

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Immunoproteomic analysis of Trichinella spiralis and Trichinella britovi excretory-secretory muscle larvae proteins recognized by sera from humans infected with Trichinella

Sylwia Grzelak, Anna Stachyra, Jerzy Stefaniak, Karolina Mrówka, Bożena Moskwa, Justyna Bień-Kalinowska

published 05 Nov 2020

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Detection of SARS-CoV-2 from raw patient samples by coupled high temperature reverse transcription and amplification

Johannes W. P. Kuiper, Timo Baade, Marcel Kremer, Ramon Kranaster, Linda Irmisch, Marcus Schuchmann, Johannes Zander, Andreas Marx, Christof R. Hauck

published 02 Nov 2020

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The values of coagulation function in COVID-19 patients

Xin Jin, Yongwei Duan, Tengfei Bao, Junjuan Gu, Yawen Chen, Yuanyuan Li, Shi Mao, Yongfeng Chen, Wen Xie

published 29 Oct 2020

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