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Primary cells

Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells

Olaf Voets, Frans Tielen, Edo Elstak, Julian Benschop, Max Grimbergen, Jan Stallen, Richard Janssen, Andre van Marle, Christian Essrich

published 11 Aug 2017

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The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-α) in thoracic ossification of the ligamentum flavum

Chi Zhang, Zhongqiang Chen, Xiangyu Meng, Mengtao Li, Li Zhang, Ann Huang

published 02 Jun 2017

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ESCDL-1, a new cell line derived from chicken embryonic stem cells, supports efficient replication of Mardiviruses

Jean-François Vautherot, Christian Jean, Laetitia Fragnet-Trapp, Sylvie Rémy, Danièle Chabanne-Vautherot, Guillaume Montillet, Aurélie Fuet, Caroline Denesvre, Bertrand Pain

published 13 Apr 2017

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The single nucleotide variant rs12722489 determines differential estrogen receptor binding and enhancer properties of an IL2RA intronic region

Marina A. Afanasyeva, Lidia V. Putlyaeva, Denis E. Demin, Ivan V. Kulakovskiy, Ilya E. Vorontsov, Marina V. Fridman, Vsevolod J. Makeev, Dmitry V. Kuprash, Anton M. Schwartz

published 24 Feb 2017

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The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells

Clarence T. Sasaki, Julia Toman, Dimitra Vageli

published 14 Dec 2016

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HCMV Displays a Unique Transcriptome of Immunomodulatory Genes in Primary Monocyte-Derived Cell Types

Ellen Van Damme, Kim Thys, Marianne Tuefferd, Carl Van Hove, Jeroen Aerssens, Marnix Van Loock

published 19 Oct 2016

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Primary Human Uterine Leiomyoma Cell Culture Quality Control: Some Properties of Myometrial Cells Cultured under Serum Deprivation Conditions in the Presence of Ovarian Steroids

Camila Bonazza, Sheila Siqueira Andrade, Joana Tomomi Sumikawa, Fabrício Pereira Batista, Edgar J. Paredes-Gamero, Manoel J. B. C. Girão, Maria Luiza V. Oliva, Rodrigo Aquino Castro

published 08 Jul 2016

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Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation

Patricia Freund, Edit A. Porpaczy, Trang Le, Michaela Gruber, Clemens Pausz, Philipp Staber, Ulrich Jäger, Katrina Vanura

published 01 Jun 2016

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Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial

Deepti Saxena, Michael Spino, Fernando Tricta, John Connelly, Bernadette M. Cracchiolo, Axel-Rainer Hanauske, Darlene D’Alliessi Gandolfi, Michael B. Mathews, Jonathan Karn, Bart Holland, Myung Hee Park, Tsafi Pe’ery, Paul E. Palumbo, Hartmut M. Hanauske-Abel

published 18 May 2016

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Drug Repositioning for Cancer Therapy Based on Large-Scale Drug-Induced Transcriptional Signatures

Haeseung Lee, Seungmin Kang, Wankyu Kim

published 08 Mar 2016

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Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD

Kathryn R. Bowles, Simon P. Brooks, Stephen B. Dunnett, Lesley Jones

published 14 Dec 2015

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Immortalization of Fetal Bovine Colon Epithelial Cells by Expression of Human Cyclin D1, Mutant Cyclin Dependent Kinase 4, and Telomerase Reverse Transcriptase: An In Vitro Model for Bacterial Infection

Kengo Kuroda, Tohru Kiyono, Emiko Isogai, Mizuki Masuda, Moe Narita, Katsuya Okuno, Yukako Koyanagi, Tomokazu Fukuda

published 01 Dec 2015

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In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells

Sarada Devi Ramachandran, Katharina Schirmer, Bernhard Münst, Stefan Heinz, Shahrouz Ghafoory, Stefan Wölfl, Katja Simon-Keller, Alexander Marx, Cristina Ionica Øie, Matthias P. Ebert, Heike Walles, Joris Braspenning, Katja Breitkopf-Heinlein

published 21 Oct 2015

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