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Precision medicine

Advancing clinical cohort selection with genomics analysis on a distributed platform

Jaclyn M. Smith, Melvin Lathara, [ ... ], Christopher T. Denny

Discovery of actionable genetic alterations with targeted panel sequencing in children with relapsed or refractory solid tumors

Ji Won Lee, Nayoung K. D. Kim, [ ... ], Woong-Yang Park

Drug sensitivity prediction with high-dimensional mixture regression

Qianyun Li, Runmin Shi, Faming Liang

Data model harmonization for the All Of Us Research Program: Transforming i2b2 data into the OMOP common data model

Jeffrey G. Klann, Matthew A. H. Joss, Kevin Embree, Shawn N. Murphy

Thought leader perspectives on benefits and harms in precision medicine research

Laura M. Beskow, Catherine M. Hammack, Kathleen M. Brelsford

Comprehensive benchmarking of SNV callers for highly admixed tumor data

Regina Bohnert, Sonia Vivas, Gunther Jansen

Model-based optimization approaches for precision medicine: A case study in presynaptic dopamine overactivity

Kai-Cheng Hsu, Feng-Sheng Wang

A Survey of U.S Adults’ Opinions about Conduct of a Nationwide Precision Medicine Initiative® Cohort Study of Genes and Environment

David J. Kaufman, Rebecca Baker, [ ... ], Kathy L. Hudson

Lollipops in the Clinic: Information Dense Mutation Plots for Precision Medicine

Jeremy J. Jay, Cory Brouwer

Conducting Precision Medicine Research with African Americans

Chanita Hughes Halbert, Jasmine McDonald, [ ... ], Melanie Jefferson

Addressing Loss of Efficiency Due to Misclassification Error in Enriched Clinical Trials for the Evaluation of Targeted Therapies Based on the Cox Proportional Hazards Model

Chen-An Tsai, Kuan-Ting Lee, Jen-pei Liu

Targeted Next-Generation Sequencing Revealed Novel Mutations in Chinese Ataxia Telangiectasia Patients: A Precision Medicine Perspective

Zhao Chen, Wei Ye, [ ... ], Hong Jiang

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