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Polymerases

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era

Santiago Montes-Moreno, Mark J. Routbort, Elijah J. Lohman, Bedia A. Barkoh, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Rajesh R. Singh, L. Jeffrey Medeiros, Raja Luthra, Keyur P. Patel

published 17 Sep 2018

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Cellular reagents for diagnostics and synthetic biology

Sanchita Bhadra, Arti Pothukuchy, Raghav Shroff, Austin W. Cole, Michelle Byrom, Jared W. Ellefson, Jimmy D. Gollihar, Andrew D. Ellington

published 15 Aug 2018

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Optimization of multiplex quantitative polymerase chain reaction based on response surface methodology and an artificial neural network-genetic algorithm approach

Ping Pan, Weifeng Jin, Xiaohong Li, Yi Chen, Jiahui Jiang, Haitong Wan, Daojun Yu

published 25 Jul 2018

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A new targeted capture method using bacterial artificial chromosome (BAC) libraries as baits for sequencing relatively large genes

Kae Koganebuchi, Takashi Gakuhari, Hirohiko Takeshima, Kimitoshi Sato, Kiyotaka Fujii, Toshihiro Kumabe, Satoshi Kasagi, Takehiro Sato, Atsushi Tajima, Hiroki Shibata, Motoyuki Ogawa, Hiroki Oota

published 12 Jul 2018

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Modelling of the breadth of expression from promoter architectures identifies pro-housekeeping transcription factors

Lukasz Huminiecki

published 21 Jun 2018

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Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation

Amit Bhardwaj, Debarghya Ghose, Krishan Gopal Thakur, Dipak Dutta

published 20 Jun 2018

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Variable termination sites of DNA polymerases encountering a DNA–protein cross-link

Anna V. Yudkina, Antonina P. Dvornikova, Dmitry O. Zharkov

published 01 Jun 2018

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On an algorithmic definition for the components of the minimal cell

Octavio Martínez, M. Humberto Reyes-Valdés

published 01 Jun 2018

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Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens

Mudra Hegde, Christine Strand, Ruth E. Hanna, John G. Doench

published 25 May 2018

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ER-positive breast cancer cells are poised for RET-mediated endocrine resistance

Sachi Horibata, Edward J. Rice, Chinatsu Mukai, Brooke A. Marks, Kelly Sams, Hui Zheng, Lynne J. Anguish, Scott A. Coonrod, Charles G. Danko

published 02 Apr 2018

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Nascent RNA signaling to yeast RNA Pol II during transcription elongation

Eva Klopf, Murielle Moes, Fabian Amman, Bob Zimmermann, Frederike von Pelchrzim, Christina Wagner, Renée Schroeder

published 23 Mar 2018

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Amino acid substitutions affecting aspartic acid 605 and valine 606 decrease the interaction strength between the influenza virus RNA polymerase PB2 '627' domain and the viral nucleoprotein

Ho-Pan Hsia, Yin-Hua Yang, Wun-Chung Szeto, Benjamin E. Nilsson, Chun-Yeung Lo, Andy Ka-Leung Ng, Ervin Fodor, Pang-Chui Shaw

published 16 Jan 2018

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Capacity of rTth polymerase to detect RNA in the presence of various inhibitors

Dongyang Cai, Ole Behrmann, Frank Hufert, Gregory Dame, Gerald Urban

published 02 Jan 2018

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