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Point mutation

Mutations in the Catalytic Loop HRD Motif Alter the Activity and Function of Drosophila Src64

Taylor C. Strong, Gurvinder Kaur, Jeffrey H. Thomas

published 23 Nov 2011

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Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development

Gerard J. P. van Westen, Jörg K. Wegner, Peggy Geluykens, Leen Kwanten, Inge Vereycken, Anik Peeters, Adriaan P. IJzerman, Herman W. T. van Vlijmen, Andreas Bender

published 23 Nov 2011

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The N-Terminal Domain and Glycosomal Localization of Leishmania Initial Acyltransferase LmDAT Are Important for Lipophosphoglycan Synthesis

Gada K. Al-Ani, Nipul Patel, Karim A. Pirani, Tongtong Zhu, Subbhalakshmi Dhalladoo, Rachel Zufferey

published 17 Nov 2011

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Antimutator Alleles of Yeast DNA Polymerase Gamma Modulate the Balance between DNA Synthesis and Excision

Françoise Foury, Karolina Szczepanowska

published 16 Nov 2011

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Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors

Jan Jakubík, Helena Janíčková, Alena Randáková, Esam E. El-Fakahany, Vladimír Doležal

published 16 Nov 2011

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Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration

Xinhua Shu, Ulrich F. O. Luhmann, Tomas S. Aleman, Susan E. Barker, Alan Lennon, Brian Tulloch, Mei Chen, Heping Xu, Samuel G. Jacobson, Robin Ali, Alan F. Wright

published 16 Nov 2011

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Mutagen-Specific Mutation Signature Determines Global microRNA Binding

Eyal Greenberg, Gideon Rechavi, Ninette Amariglio, Oz Solomon, Jacob Schachter, Gal Markel, Eran Eyal

published 09 Nov 2011

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Contribution of NFP LysM Domains to the Recognition of Nod Factors during the Medicago truncatula/Sinorhizobium meliloti Symbiosis

Sandra Bensmihen, Françoise de Billy, Clare Gough

published 08 Nov 2011

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Optimal Antiviral Switching to Minimize Resistance Risk in HIV Therapy

Rutao Luo, Michael J. Piovoso, Javier Martinez-Picado, Ryan Zurakowski

published 03 Nov 2011

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A Point Mutation in Translation Initiation Factor eIF2B Leads to Function- and Time-Specific Changes in Brain Gene Expression

Liraz Marom, Igor Ulitsky, Yuval Cabilly, Ron Shamir, Orna Elroy-Stein

published 31 Oct 2011

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Antigenic, Immunologic and Genetic Characterization of Rough Strains B.abortus RB51, B.melitensis B115 and B.melitensis B18

Rosanna Adone, Michele Muscillo, Giuseppina La Rosa, Massimiliano Francia, Michela Tarantino

published 31 Oct 2011

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Differential Sensitivity of ERBB2 Kinase Domain Mutations towards Lapatinib

Rama Krishna Kancha, Nikolas von Bubnoff, Natalie Bartosch, Christian Peschel, Richard A. Engh, Justus Duyster

published 28 Oct 2011

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Beyond Genetic Factors in Familial Amyloidotic Polyneuropathy: Protein Glycation and the Loss of Fibrinogen's Chaperone Activity

Gonçalo da Costa, Ricardo A. Gomes, Ana Guerreiro, Élia Mateus, Estela Monteiro, Eduardo Barroso, Ana V. Coelho, Ana Ponces Freire, Carlos Cordeiro

published 28 Oct 2011

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