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Point mutation

High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation

Audrey D. McConnell, Minjee Do, Tamlyn Y. Neben, Vladimir Spasojevic, Josh MacLaren, Andy P. Chen, Laurence Altobell III, John L. Macomber, Ashley D. Berkebile, Robert A. Horlick, Peter M. Bowers, David J. King

published 14 Nov 2012

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Mos1-Mediated Transgenesis to Probe Consequences of Single Gene Mutations in Variation-Rich Isolates of Caenorhabditis elegans

Maja Tarailo-Graovac, Nansheng Chen

published 14 Nov 2012

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Induced Tauopathy in a Novel 3D-Culture Model Mediates Neurodegenerative Processes: A Real-Time Study on Biochips

Diana Seidel, Dana Krinke, Heinz-Georg Jahnke, Anika Hirche, Daniel Kloß, Till G. A. Mack, Frank Striggow, Andrea Robitzki

published 07 Nov 2012

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Design of pH Sensitive Binding Proteins from the Hyperthermophilic Sso7d Scaffold

Nimish Gera, Andrew B. Hill, Dalon P. White, Ruben G. Carbonell, Balaji M. Rao

published 07 Nov 2012

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Deciphering the Roles of BamB and Its Interaction with BamA in Outer Membrane Biogenesis, T3SS Expression and Virulence in Salmonella

Fatémeh Namdari, Genaro Alejandro Hurtado-Escobar, Nadia Abed, Jérôme Trotereau, Yann Fardini, Etienne Giraud, Philippe Velge, Isabelle Virlogeux-Payant

published 05 Nov 2012

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Fibrillin-1 Mutations Causing Weill-Marchesani Syndrome and Acromicric and Geleophysic Dysplasias Disrupt Heparan Sulfate Interactions

Stuart A. Cain, Amanda McGovern, Andrew K. Baldwin, Clair Baldock, Cay M. Kielty

published 02 Nov 2012

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Towards Improvements in the Estimation of the Coalescent: Implications for the Most Effective Use of Y Chromosome Short Tandem Repeat Mutation Rates

Steven C. Bird

published 31 Oct 2012

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Role of Disulfide Cross-Linking of Mutant SOD1 in the Formation of Inclusion-Body-Like Structures

Brittany L. T. Roberts, Kinaree Patel, Hilda H. Brown, David R. Borchelt

published 31 Oct 2012

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Apparent Defect in Yeast Bud-Site Selection Due to a Specific Failure to Splice the Pre-mRNA of a Regulator of Cell-Type-Specific Transcription

Shanshan Tuo, Kenichi Nakashima, John R. Pringle

published 31 Oct 2012

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Assessing Predictors of Changes in Protein Stability upon Mutation Using Self-Consistency

Grant Thiltgen, Richard A. Goldstein

published 29 Oct 2012

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Multiple Analyses of G-Protein Coupled Receptor (GPCR) Expression in the Development of Gefitinib-Resistance in Transforming Non-Small-Cell Lung Cancer

Naoko Kuzumaki, Atsuo Suzuki, Michiko Narita, Takahiro Hosoya, Atsumi Nagasawa, Satoshi Imai, Kohei Yamamizu, Hiroshi Morita, Tsutomu Suzuki, Yohei Okada, Hirotaka James Okano, Jun K. Yamashita, Hideyuki Okano, Minoru Narita

published 29 Oct 2012

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Efficient Detection of Mediterranean β-Thalassemia Mutations by Multiplex Single-Nucleotide Primer Extension

Biljana Atanasovska, Georgi Bozhinovski, Dijana Plaseska-Karanfilska, Lyubomira Chakalova

published 26 Oct 2012

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Increased Mutability of Staphylococci in Biofilms as a Consequence of Oxidative Stress

Victoria J. Ryder, Ian Chopra, Alex J. O’Neill

published 24 Oct 2012

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