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Point mutation

Natural and Unanticipated Modifiers of RNAi Activity in Caenorhabditis elegans

Nadeem Asad, Wen Yih Aw, Lisa Timmons

published 28 Nov 2012

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Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes

Randy Hecht, Yue-Sheng Li, Jeonghoon Sun, Ed Belouski, Michael Hall, Todd Hager, Junming Yie, Wei Wang, Dwight Winters, Stephen Smith, Chris Spahr, Lei-Ting Tam, Zhongnan Shen, Shanaka Stanislaus, Narumol Chinookoswong, Yvonne Lau, Allen Sickmier, Mark Leo Michaels, Thomas Boone, Murielle M. Véniant, Jing Xu

published 27 Nov 2012

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The Optimal Mutagen Dosage to Induce Point-Mutations in Synechocystis sp. PCC6803 and Its Application to Promote Temperature Tolerance

Ulrich M. Tillich, Sandra Lehmann, Katja Schulze, Ulf Dühring, Marcus Frohme

published 21 Nov 2012

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High-Throughput Discovery of Chloroplast and Mitochondrial DNA Polymorphisms in Brassicaceae Species by ORG-EcoTILLING

Chang-Li Zeng, Guang-Yong Wang, Jian-Bo Wang, Gui-Xin Yan, Bi-Yun Chen, Kun Xu, Jun Li, Gui-Zhen Gao, Xiao-Ming Wu, Bo Zhao, Lei Liu

published 21 Nov 2012

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A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii

Jun-Ren Sun, Cherng-Lih Perng, Ming-Chin Chan, Yuji Morita, Jung-Chung Lin, Chih-Mao Su, Wei-Yao Wang, Tein-Yao Chang, Tzong-Shi Chiueh

published 14 Nov 2012

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High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation

Audrey D. McConnell, Minjee Do, Tamlyn Y. Neben, Vladimir Spasojevic, Josh MacLaren, Andy P. Chen, Laurence Altobell III, John L. Macomber, Ashley D. Berkebile, Robert A. Horlick, Peter M. Bowers, David J. King

published 14 Nov 2012

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Mos1-Mediated Transgenesis to Probe Consequences of Single Gene Mutations in Variation-Rich Isolates of Caenorhabditis elegans

Maja Tarailo-Graovac, Nansheng Chen

published 14 Nov 2012

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Induced Tauopathy in a Novel 3D-Culture Model Mediates Neurodegenerative Processes: A Real-Time Study on Biochips

Diana Seidel, Dana Krinke, Heinz-Georg Jahnke, Anika Hirche, Daniel Kloß, Till G. A. Mack, Frank Striggow, Andrea Robitzki

published 07 Nov 2012

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Design of pH Sensitive Binding Proteins from the Hyperthermophilic Sso7d Scaffold

Nimish Gera, Andrew B. Hill, Dalon P. White, Ruben G. Carbonell, Balaji M. Rao

published 07 Nov 2012

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Deciphering the Roles of BamB and Its Interaction with BamA in Outer Membrane Biogenesis, T3SS Expression and Virulence in Salmonella

Fatémeh Namdari, Genaro Alejandro Hurtado-Escobar, Nadia Abed, Jérôme Trotereau, Yann Fardini, Etienne Giraud, Philippe Velge, Isabelle Virlogeux-Payant

published 05 Nov 2012

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Fibrillin-1 Mutations Causing Weill-Marchesani Syndrome and Acromicric and Geleophysic Dysplasias Disrupt Heparan Sulfate Interactions

Stuart A. Cain, Amanda McGovern, Andrew K. Baldwin, Clair Baldock, Cay M. Kielty

published 02 Nov 2012

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Towards Improvements in the Estimation of the Coalescent: Implications for the Most Effective Use of Y Chromosome Short Tandem Repeat Mutation Rates

Steven C. Bird

published 31 Oct 2012

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Role of Disulfide Cross-Linking of Mutant SOD1 in the Formation of Inclusion-Body-Like Structures

Brittany L. T. Roberts, Kinaree Patel, Hilda H. Brown, David R. Borchelt

published 31 Oct 2012

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