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Point mutation

Enhancing the thermostability of Streptomyces cyaneofuscatus strain Ms1 tyrosinase by multi-factors rational design and molecular dynamics simulations

Zhengtao Li, Chen Zhao, Duanhua Li, Lu Wang

published 20 Jul 2023

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Dermokine mutations contribute to epithelial-mesenchymal transition and advanced melanoma through ERK/MAPK pathways

Wenqiong Ma, Zexiu Wu, Mazaher Maghsoudloo, Iqra Ijaz, Marzieh Dehghan Shasaltaneh, Yuqin Zhang, Qiao Weng, Junjiang Fu, Saber Imani, Qing Lian Wen

published 11 Jul 2023

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An amino acid substitution in HCV core antigen limits its use as a reliable measure of HCV infection compared with HCV RNA

Payuda Hansoongnern, Pornpitra Pratedrat, Pornjarim Nilyanimit, Rujipat Wasitthankasem, Nawarat Posuwan, Nasamon Wanlapakorn, Kanchanok Kodchakorn, Prachya Kongtawelert, Napaporn Pimsing, Yong Poovorawan

published 29 Jun 2023

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Impact of highly deleterious non-synonymous polymorphisms on GRIN2A protein’s structure and function

Ishtiaque Ahammad, Tabassum Binte Jamal, Arittra Bhattacharjee, Zeshan Mahmud Chowdhury, Suparna Rahman, Md Rakibul Hassan, Mohammad Uzzal Hossain, Keshob Chandra Das, Chaman Ara Keya, Md Salimullah

published 15 Jun 2023

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Altered GC- and AT-biased genotypes of Ophiocordyceps sinensis in the stromal fertile portions and ascospores of natural Cordyceps sinensis

Yu-Ling Li, Ling Gao, Yi-Sang Yao, Xiu-Zhang Li, Zi-Mei Wu, Ning-Zhi Tan, Zhou-Qing Luo, Wei-Dong Xie, Jian-Yong Wu, Jia-Shi Zhu

published 08 Jun 2023

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Reconsideration of importance of the point mutation L982W in the voltage-sensitive sodium channel of the pyrethroid resistant Aedes aegypti (L.)(Diptera: Culicidae) in Vietnam

Hitoshi Kawada, Yukiko Higa, Shinji Kasai

published 17 May 2023

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Modeling SARS-CoV-2 nucleotide mutations as a stochastic process

Maverick Lim Kai Rong, Ercan Engin Kuruoglu, Wai Kin Victor Chan

published 28 Apr 2023

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Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability

Aleksi Sutinen, Dirk Paffenholz, Giang Thi Tuyet Nguyen, Salla Ruskamo, Andrew E. Torda, Petri Kursula

published 14 Apr 2023

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Using AlphaFold to predict the impact of single mutations on protein stability and function

Marina A. Pak, Karina A. Markhieva, Mariia S. Novikova, Dmitry S. Petrov, Ilya S. Vorobyev, Ekaterina S. Maksimova, Fyodor A. Kondrashov, Dmitry N. Ivankov

published 16 Mar 2023

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Clonal isolates of Treponema pallidum subsp. pallidum Nichols provide evidence for the occurrence of microevolution during experimental rabbit infection and in vitro culture

Diane G. Edmondson, Bridget D. De Lay, Blake M. Hanson, Lindsay E. Kowis, Steven J. Norris

published 14 Mar 2023

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Research experimental design for the construction and identification of the pGEX-BCKD-E4A recombinant point-mutant plasmid

Tiannan Zhou, Huixian Wei, Jinjun Wang

published 24 Feb 2023

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Molecular evidence of parallel evolution in a cyanophage

Jesslyn Tjendra, Julia E. Storesund, Håkon Dahle, Ruth-Anne Sandaa, Selina Våge

published 09 Feb 2023

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Investigating the origin of subtelomeric and centromeric AT-rich elements in Aspergillus flavus

Arthur J. Lustig

published 09 Feb 2023

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