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Point mutation

Clinical and molecular characteristics associated with high PD-L1 expression in EGFR-mutated lung adenocarcinoma

Jeremy Slomka, Hugo Berthou, Audrey Mansuet-Lupo, Hélène Blons, Elizabeth Fabre, Ivan Lerner, Bastien Rance, Marco Alifano, Jeanne Chapron, Gary Birsen, Laure Gibault, Jennifer Arrondeau, Karen Leroy, Marie Wislez

published 07 Nov 2024

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Overcoming problematic growth phenotypes in organoids from patients with monogenic GI disease

Katlynn Bugda Gwilt, Jay R. Thiagarajah

published 04 Nov 2024

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Bioinformatics design of peptide binding to the human cardiac troponin I (cTnI) in biosensor development for myocardial infarction diagnosis

Muhammad Miftah Jauhar, Filasta Rachel Damairetha, Etik Mardliyati, Mokhamad Fakhrul Ulum, Putri Hawa Syaifie, Fahmi Fahmi, Ardianto Satriawan, Wervyan Shalannanda, Isa Anshori

published 22 Oct 2024

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Elucidating the role of MLL1 nsSNPs: Structural and functional alterations and their contribution to leukemia development

Hakeemah H. Al-nakhle, Hind S. Yagoub, Rahaf Y. Alrehaili, Ola A. Shaqroon, Minna K. Khan, Ghaidaa S. Alsharif

published 15 Oct 2024

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Analysis of low-density lipoprotein receptor gene mutations in a family with familial hypercholesterolemia

Ya-nan Hu, Min Wu, Hong-ping Yu, Qiu-yan Wu, Ying Chen, Jian-Hui Zhang, Dan-dan Ruan, Yan-ping Zhang, Jing Zou, Li Zhang, Xin-fu Lin, Zhu-ting Fang, Li-Sheng Liao, Fan Lin, Hong Li, Jie-Wei Luo

published 11 Oct 2024

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A new amino acid substitution in the MvALS1 gene of metsulfuron-methyl resistant biotypes Monochoria vaginalis (Burm. f.) C. Presl from West Java, Indonesia

Kansa Dianti Putri, Dwi Guntoro, Sintho Wahyuning Ardie, Hariyadi

published 04 Oct 2024

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Comparative genomic landscape of lower-grade glioma and glioblastoma

Xinxin Sun, Qingbin Jia, Kun Li, Conghui Tian, Lili Yi, Lili Yan, Juan Zheng, Xiaodong Jia, Mingliang Gu

published 29 Aug 2024

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Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay

Dinh Thi Thao, Nguyen Phu Thanh, Dong Van Quyen, Ly Tuan Khai, Le Huu Song, Ngo Tat Trung

published 28 Aug 2024

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One-pot Golden Gate Assembly of an avian infectious bronchitis virus reverse genetics system

Katharina Bilotti, Sarah Keep, Andrew P. Sikkema, John M. Pryor, James Kirk, Katalin Foldes, Nicole Doyle, Ge Wu, Graham Freimanis, Giulia Dowgier, Oluwapelumi Adeyemi, S. Kasra Tabatabaei, Gregory J. S. Lohman, Erica Bickerton

published 25 Jul 2024

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Design and characterization of hyperactive mutants of the Agrobacterium tumefaciens telomere resolvase, TelA

Shu Hui Huang, Kayla Abrametz, Siobhan L. McGrath, Kerri Kobryn

published 25 Jul 2024

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An in silico investigation on the binding site preference of PD-1 and PD-L1 for designing antibodies for targeted cancer therapy

Sarah Abdolmaleki, Mazdak Ganjalikhani hakemi, Mohamad Reza Ganjalikhany

published 25 Jul 2024

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Mutation accumulation in H. sapiens F508del CFTR countermands dN/dS type genomic analysis

Jeong S. Hong, Janice M. Tindall, Samuel R. Tindall, Eric J. Sorscher

published 18 Jul 2024

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Impact of mutations in the mtrR, rpdlVD and rrl genes on azithromycin resistance in Neisseria gonorrhoeae

Florian Mauffrey, Fabrice Poncet, Damien Jacot, Gilbert Greub, Patrice Nordmann, Dominique S. Blanc

published 16 Jul 2024

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