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Point mutation

No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells

Parisa Javidi-Parsijani, Guoguang Niu, Meghan Davis, Pin Lu, Anthony Atala, Baisong Lu

published 11 May 2017

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Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ

Kiani A. J. Arkus Gardner, Masaki Osawa, Harold P. Erickson

published 26 Apr 2017

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Various mutations compensate for a deleterious lacZα insert in the replication enhancer of M13 bacteriophage

Emily M. Zygiel, Karen A. Noren, Marta A. Adamkiewicz, Richard J. Aprile, Heather K. Bowditch, Christine L. Carroll, Maria Abigail S. Cerezo, Adelle M. Dagher, Courtney R. Hebert, Lauren E. Hebert, Gloria M. Mahame, Stephanie C. Milne, Kelly M. Silvestri, Sara E. Sutherland, Alexandria M. Sylvia, Caitlyn N. Taveira, David J. VanValkenburgh, Christopher J. Noren, Marilena Fitzsimons Hall

published 26 Apr 2017

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A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model

Xuan Yuan, Zhe Li, Andrea C. Baines, Eleni Gavriilaki, Zhaohui Ye, Zhexing Wen, Evan M. Braunstein, Leslie G. Biesecker, Linzhao Cheng, Xinzhong Dong, Robert A. Brodsky

published 25 Apr 2017

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A new model mimicking persistent HBV e antigen-negative infection using covalently closed circular DNA in immunocompetent mice

Lei Wang, Min Cao, Qing Lu Wei, Zhong Hua Zhao, Qin Xiang, Hui Juan Wang, Hua Tang Zhang, Guo Qi Lai

published 20 Apr 2017

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Correlation of EGFR or KRAS mutation status with ¹⁸F-FDG uptake on PET-CT scan in lung adenocarcinoma

Kazuya Takamochi, Kaoru Mogushi, Hideya Kawaji, Kota Imashimizu, Mariko Fukui, Shiaki Oh, Masayoshi Itoh, Yoshihide Hayashizaki, Weijey Ko, Masao Akeboshi, Kenji Suzuki

published 19 Apr 2017

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Mutational spectrum of Chinese LGMD patients by targeted next-generation sequencing

Meng Yu, Yiming Zheng, Suqin Jin, Qiang Gang, Qingqing Wang, Peng Yu, He Lv, Wei Zhang, Yun Yuan, Zhaoxia Wang

published 12 Apr 2017

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Mechanisms of glycosylase induced genomic instability

Daniel E. Eyler, Kylie A. Burnham, Thomas E. Wilson, Patrick J. O’Brien

published 23 Mar 2017

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Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer

Rebecca F. Lowdon, Ting Wang

published 23 Mar 2017

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Prognostic value of plasma EGFR ctDNA in NSCLC patients treated with EGFR-TKIs

Chengjuan Zhang, Bing Wei, Peng Li, Ke Yang, Zhizhong Wang, Jie Ma, Yongjun Guo

published 23 Mar 2017

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Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function

Mio Yumura, Natsuko Yamamoto, Katsushi Yokoyama, Hirotada Mori, Tetsuya Yomo, Norikazu Ichihashi

published 22 Mar 2017

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TP53 alterations in primary and secondary Sézary syndrome: A diagnostic tool for the assessment of malignancy in patients with erythroderma

Audrey Gros, Elodie Laharanne, Marie Vergier, Martina Prochazkova-Carlotti, Anne Pham-Ledard, Thomas Bandres, Sandrine Poglio, Sabine Berhouet, Béatrice Vergier, Jean-Philippe Vial, Edith Chevret, Marie Beylot-Barry, Jean-Philippe Merlio

published 16 Mar 2017

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Impact of genetic variation on three dimensional structure and function of proteins

Roshni Bhattacharya, Peter W. Rose, Stephen K. Burley, Andreas Prlić

published 15 Mar 2017

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