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Point mutation

Fourth-Generation Epac-Based FRET Sensors for cAMP Feature Exceptional Brightness, Photostability and Dynamic Range: Characterization of Dedicated Sensors for FLIM, for Ratiometry and with High Affinity

Jeffrey Klarenbeek, Joachim Goedhart, [ ... ], Kees Jalink

CRISPR Interference Directs Strand Specific Spacer Acquisition

Daan C. Swarts, Cas Mosterd, Mark W. J. van Passel, Stan J. J. Brouns

Thermal stability and kinetic constants for 129 variants of a family 1 glycoside hydrolase reveal that enzyme activity and stability can be separately designed

Dylan Alexander Carlin, Siena Hapig-Ward, [ ... ], Justin B. Siegel

Evaluation of Genetic Mutations Associated with Mycobacterium tuberculosis Resistance to Amikacin, Kanamycin and Capreomycin: A Systematic Review

Sophia B. Georghiou, Marisa Magana, [ ... ], Timothy C. Rodwell

Strand Invasion Based Amplification (SIBA®): A Novel Isothermal DNA Amplification Technology Demonstrating High Specificity and Sensitivity for a Single Molecule of Target Analyte

Mark J. Hoser, Hannu K. Mansukoski, Scott W. Morrical, Kevin E. Eboigbodin

Familial Occurrence of Systemic Mast Cell Activation Disease

Gerhard J. Molderings, Britta Haenisch, [ ... ], Markus M. Nöthen

Efficient Genome Engineering of Toxoplasma gondii Using CRISPR/Cas9

Saima M. Sidik, Caroline G. Hackett, [ ... ], Sebastian Lourido

Dystrophin Gene Mutation Location and the Risk of Cognitive Impairment in Duchenne Muscular Dystrophy

Peter J. Taylor, Grant A. Betts, [ ... ], Michael F. Buckley

Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies

Manish Sarkar, Soham Saha

Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints

Douglas D. Axe, Brendan W. Dixon, Philip Lu

CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review

Haris Babačić, Aditi Mehta, Olivia Merkel, Benedikt Schoser

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

Asimina Hiona, Alberto Sanz, [ ... ], Christiaan Leeuwenburgh

Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays

Leena Pohjala, Age Utt, [ ... ], Päivi Tammela

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