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Point mutation

Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer

Sindhu Nair, Hoa Q. Trummell, Rajani Rajbhandari, Nanda K. Thudi, Susan E. Nozell, Jason M. Warram, Christopher D. Willey, Eddy S. Yang, William J. Placzek, James A. Bonner, Markus Bredel

published 18 Feb 2020

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Clinical significance of EGFR mutation types in lung adenocarcinoma: A multi-centre Korean study

Hee-Young Yoon, Jeong-Seon Ryu, Yun Su Sim, Dojin Kim, Sung Yong Lee, Juwhan Choi, Sojung Park, Yon Ju Ryu, Jin Hwa Lee, Jung Hyun Chang

published 13 Feb 2020

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Tks5 SH3 domains exhibit differential effects on invadopodia development

Christina Daly, Brewer Logan, Joseph Breeyear, Kelley Whitaker, Maryam Ahmed, Darren F. Seals

published 30 Jan 2020

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Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

Anthony Crown, Luke McAlary, Eric Fagerli, Hilda Brown, Justin J. Yerbury, Ahmad Galaleldeen, Neil R. Cashman, David R. Borchelt, Jacob I. Ayers

published 30 Jan 2020

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Antimicrobial resistance patterns and molecular resistance markers of Campylobacter jejuni isolates from human diarrheal cases

Mohamed Elhadidy, Mohamed Medhat Ali, Ayman El-Shibiny, William G. Miller, Walid F. Elkhatib, Nadine Botteldoorn, Katelijne Dierick

published 17 Jan 2020

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Pan-cancer analysis of somatic mutations and epigenetic alterations in insulated neighbourhood boundaries

Pietro Pinoli, Eirini Stamoulakatou, An-Phi Nguyen, María Rodríguez Martínez, Stefano Ceri

published 16 Jan 2020

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First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

Gregory Brubaker, Shuhui W. Lorkowski, Kailash Gulshan, Stanley L. Hazen, Valentin Gogonea, Jonathan D. Smith

published 16 Jan 2020

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Deep2Full: Evaluating strategies for selecting the minimal mutational experiments for optimal computational predictions of deep mutational scan outcomes

C. K. Sruthi, Meher Prakash

published 10 Jan 2020

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Longitudinal monitoring of KRAS-mutated circulating tumor DNA enables the prediction of prognosis and therapeutic responses in patients with pancreatic cancer

Fumiaki Watanabe, Koichi Suzuki, Sawako Tamaki, Iku Abe, Yuhei Endo, Yuji Takayama, Hideki Ishikawa, Nao Kakizawa, Masaaki Saito, Kazushige Futsuhara, Hiroshi Noda, Fumio Konishi, Toshiki Rikiyama

published 31 Dec 2019

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Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions

Kyoungmi Kim, David Hessl, Jamie L. Randol, Glenda M. Espinal, Andrea Schneider, Dragana Protic, Elber Yuksel Aydin, Randi J. Hagerman, Paul J. Hagerman

published 31 Dec 2019

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AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

Arne A. N. Bruyneel, Alexandre R. Colas, Ioannis Karakikes, Mark Mercola

published 26 Dec 2019

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Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients

Le Son Tran, Hong-Anh Thi Pham, Vu-Uyen Tran, Thanh-Truong Tran, Anh-Thu Huynh Dang, Dinh-Thong Le, Son-Lam Nguyen, Ngoc-Vu Nguyen, Trieu-Vu Nguyen, Binh Thanh Vo, Hong-Thuy Thi Dao, Nguyen Huu Nguyen, Tam Huu Tran, Chu Van Nguyen, Phuong Cam Pham, Anh Tuan Dang-Mai, Thien Kim Dinh-Nguyen, Van Hieu Phan, Thanh-Thuy Thi Do, Kiet Truong Dinh, Han Ngoc Do, Minh-Duy Phan, Hoa Giang, Hoai-Nghia Nguyen

published 16 Dec 2019

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Mutation analysis of annual sediment discharge at Wu Long station in Wu Jiang River Basin from 1960 to 2016

Peng Chen, Guangming Tan, Jinyun Deng, Quanxi Xu, Rouxin Tang

published 16 Dec 2019

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