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Point mutation

The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer’s Disease in SH-SY5Y cells

Antoine Guyon, Joël Rousseau, Gabriel Lamothe, Jacques P. Tremblay

published 28 Dec 2020

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Assessment of software methods for estimating protein-protein relative binding affinities

Tawny R. Gonzalez, Kyle P. Martin, Jonathan E. Barnes, Jagdish Suresh Patel, F. Marty Ytreberg

published 21 Dec 2020

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5,5-Dialkylluciferins are thermal stable substrates for bioluminescence-based detection systems

Ce Shi, Michael P. Killoran, Mary P. Hall, Paul Otto, Monika G. Wood, Ethan Strauss, Lance P. Encell, Thomas Machleidt, Keith V. Wood, Thomas A. Kirkland

published 14 Dec 2020

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Improved yellow-green split fluorescent proteins for protein labeling and signal amplification

Shuqin Zhou, Siyu Feng, David Brown, Bo Huang

published 23 Nov 2020

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Static all-atom energetic mappings of the SARS-Cov-2 spike protein and dynamic stability analysis of “Up” versus “Down” protomer states

Michael H. Peters, Oscar Bastidas, Daniel S. Kokron, Christopher E. Henze

published 10 Nov 2020

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Trends in de-lousing of Norwegian farmed salmon from 2000–2019—Consumption of medicines, salmon louse resistance and non-medicinal control methods

Elena Myhre Jensen, Tor Einar Horsberg, Sigmund Sevatdal, Kari Olli Helgesen

published 29 Oct 2020

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Deviation from Mendelian transmission of autosomal SNPs can be used to estimate germline mutations in humans exposed to ionizing radiation

Hugo Pereira Leite Filho, Irene Plaza Pinto, Lorraynne Guimarães Oliveira, Emília Oliveira Alves Costa, Alex Silva da Cruz, Daniela de Melo e Silva, Claudio Carlos da Silva, Alexandre Rodrigues Caetano, Aparecido Divino da Cruz

published 27 Oct 2020

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Evaluating the prevalence and risk factors for macrolide resistance in Mycoplasma genitalium using a newly developed qPCR assay

Joyce F. Braam, David J. Hetem, Clarissa E. Vergunst, Sophie Kuizenga Wessel, Martijn S. van Rooijen, Roel H. T. Nijhuis, Maarten F. Schim van der Loeff, Alje P. van Dam, Sylvia M. Bruisten

published 20 Oct 2020

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Molecular investigations on a chimeric strain of Staphylococcus aureus sequence type 80

Darius Gawlik, Antje Ruppelt-Lorz, Elke Müller, Annett Reißig, Helmut Hotzel, Sascha D. Braun, Bo Söderquist, Albrecht Ziegler-Cordts, Claudia Stein, Mathias W. Pletz, Ralf Ehricht, Stefan Monecke

published 14 Oct 2020

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Generation of a conditional mutant knock-in under the control of the natural promoter using CRISPR-Cas9 and Cre-Lox systems

Vijay S. Thakur, Scott M. Welford

published 02 Oct 2020

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CRISPR/Cas9-mediated correction of mutated copper transporter ATP7B

Michael Pöhler, Sarah Guttmann, Oksana Nadzemova, Malte Lenders, Eva Brand, Andree Zibert, Hartmut H. Schmidt, Vanessa Sandfort

published 30 Sep 2020

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Evaluation of the GenoType NTM-DR assay performance for the identification and molecular detection of antibiotic resistance in Mycobacterium abscessus complex

Nicolas Bouzinbi, Olivier Marcy, Thibault Bertolotti, Raphael Chiron, Pascale Bemer, Martine Pestel-Caron, Olivia Peuchant, Hélène Guet-Revillet, Marie-Sarah Fangous, Geneviève Héry-Arnaud, Abdoul-Salam Ouedraogo, Anne-Laure Bañuls, Sylvain Godreuil

published 25 Sep 2020

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Ancient mitochondrial DNA pathogenic variants putatively associated with mitochondrial disease

Draga Toncheva, Dimitar Serbezov, Sena Karachanak-Yankova, Desislava Nesheva

published 24 Sep 2020

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