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Point mutation

The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer’s Disease in SH-SY5Y cells

Antoine Guyon, Joël Rousseau, Gabriel Lamothe, Jacques P. Tremblay

Assessment of software methods for estimating protein-protein relative binding affinities

Tawny R. Gonzalez, Kyle P. Martin, [ ... ], F. Marty Ytreberg

5,5-Dialkylluciferins are thermal stable substrates for bioluminescence-based detection systems

Ce Shi, Michael P. Killoran, [ ... ], Thomas A. Kirkland

Improved yellow-green split fluorescent proteins for protein labeling and signal amplification

Shuqin Zhou, Siyu Feng, David Brown, Bo Huang

Static all-atom energetic mappings of the SARS-Cov-2 spike protein and dynamic stability analysis of “Up” versus “Down” protomer states

Michael H. Peters, Oscar Bastidas, Daniel S. Kokron, Christopher E. Henze

Trends in de-lousing of Norwegian farmed salmon from 2000–2019—Consumption of medicines, salmon louse resistance and non-medicinal control methods

Elena Myhre Jensen, Tor Einar Horsberg, Sigmund Sevatdal, Kari Olli Helgesen

Deviation from Mendelian transmission of autosomal SNPs can be used to estimate germline mutations in humans exposed to ionizing radiation

Hugo Pereira Leite Filho, Irene Plaza Pinto, [ ... ], Aparecido Divino da Cruz

Evaluating the prevalence and risk factors for macrolide resistance in Mycoplasma genitalium using a newly developed qPCR assay

Joyce F. Braam, David J. Hetem, [ ... ], Sylvia M. Bruisten

Molecular investigations on a chimeric strain of Staphylococcus aureus sequence type 80

Darius Gawlik, Antje Ruppelt-Lorz, [ ... ], Stefan Monecke

Generation of a conditional mutant knock-in under the control of the natural promoter using CRISPR-Cas9 and Cre-Lox systems

Vijay S. Thakur, Scott M. Welford

CRISPR/Cas9-mediated correction of mutated copper transporter ATP7B

Michael Pöhler, Sarah Guttmann, [ ... ], Vanessa Sandfort

Evaluation of the GenoType NTM-DR assay performance for the identification and molecular detection of antibiotic resistance in Mycobacterium abscessus complex

Nicolas Bouzinbi, Olivier Marcy, [ ... ], Sylvain Godreuil

Ancient mitochondrial DNA pathogenic variants putatively associated with mitochondrial disease

Draga Toncheva, Dimitar Serbezov, Sena Karachanak-Yankova, Desislava Nesheva

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