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Point mutation

High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation

Audrey D. McConnell, Minjee Do, [ ... ], David J. King

JAK2 Exon 14 Deletion in Patients with Chronic Myeloproliferative Neoplasms

Wanlong Ma, Hagop Kantarjian, [ ... ], Maher Albitar

Engineering Genetically Encoded Nanosensors for Real-Time In Vivo Measurements of Citrate Concentrations

Jennifer C. Ewald, Sabrina Reich, [ ... ], Nicola Zamboni

Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold Optimization

Matthew D. Smith, Matthew A. Rosenow, [ ... ], John C. Chaput

Glucokinase Gene Mutations: Structural and Genotype-Phenotype Analyses in MODY Children from South Italy

Nadia Tinto, Adriana Zagari, [ ... ], Lucia Sacchetti

Novel Mutations in ACVR1 Result in Atypical Features in Two Fibrodysplasia Ossificans Progressiva Patients

Kirsten A. Petrie, Wen Hwa Lee, [ ... ], James T. Triffitt

The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins

Hiroyuki O. Ishikawa, Aiguo Xu, [ ... ], Kenneth D. Irvine

Routine Multiplex Mutational Profiling of Melanomas Enables Enrollment in Genotype-Driven Therapeutic Trials

Christine M. Lovly, Kimberly Brown Dahlman, [ ... ], William Pao

Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution Interventions

Yi Li, Saurabh Mendiratta, [ ... ], Leonidas Bleris

Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif?

Dominic P. Byrne, Caroline Dart, Daniel J. Rigden

New Mutations in Chronic Lymphocytic Leukemia Identified by Target Enrichment and Deep Sequencing

Elena Doménech, Gonzalo Gómez-López, [ ... ], Margarita Sánchez-Beato

CBL Is Frequently Altered in Lung Cancers: Its Relationship to Mutations in MET and EGFR Tyrosine Kinases

Yi-Hung Carol Tan, Soundararajan Krishnaswamy, [ ... ], Ravi Salgia

Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer

Andrea Sartore-Bianchi, Federica Di Nicolantonio, [ ... ], Salvatore Siena

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