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Point mutation

Targeted KRAS Mutation Assessment on Patient Tumor Histologic Material in Real Time Diagnostics

Vassiliki Kotoula, Elpida Charalambous, Bart Biesmans, Andigoni Malousi, Eleni Vrettou, George Fountzilas, George Karkavelas

published 04 Nov 2009

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Screening for Microsatellite Instability Identifies Frequent 3′-Untranslated Region Mutation of the RB1-Inducible Coiled-Coil 1 Gene in Colon Tumors

Bogdan C. Paun, Yulan Cheng, Barbara A. Leggett, Joanne Young, Stephen J. Meltzer, Yuriko Mori

published 02 Nov 2009

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Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block

Franck C. Chatelain, Sabrina Gazzarrini, Yuichiro Fujiwara, Cristina Arrigoni, Courtney Domigan, Giuseppina Ferrara, Carlos Pantoja, Gerhard Thiel, Anna Moroni, Daniel L. Minor Jr.

published 16 Oct 2009

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Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Anshuman Dixit, Lin Yi, Ragul Gowthaman, Ali Torkamani, Nicholas J. Schork, Gennady M. Verkhivker

published 16 Oct 2009

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An Enhanced Single Base Extension Technique for the Analysis of Complex Viral Populations

Dale R. Webster, Armin G. Hekele, Adam S. Lauring, Kael F. Fischer, Hao Li, Raul Andino, Joseph L. DeRisi

published 16 Oct 2009

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Point Mutations in GLI3 Lead to Misregulation of its Subcellular Localization

Sybille Krauß, Joyce So, Melanie Hambrock, Andrea Köhler, Melanie Kunath, Constance Scharff, Martina Wessling, Karl-Heinz Grzeschik, Rainer Schneider, Susann Schweiger

published 15 Oct 2009

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Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer

Andrea Sartore-Bianchi, Federica Di Nicolantonio, Michele Nichelatti, Francesca Molinari, Sara De Dosso, Piercarlo Saletti, Miriam Martini, Tiziana Cipani, Giovanna Marrapese, Luca Mazzucchelli, Simona Lamba, Silvio Veronese, Milo Frattini, Alberto Bardelli, Salvatore Siena

published 02 Oct 2009

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BtubA-BtubB Heterodimer Is an Essential Intermediate in Protofilament Assembly

Christopher A. Sontag, Harvey Sage, Harold P. Erickson

published 29 Sep 2009

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Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes

Konstantin A. Tsetsarkin, Charles E. McGee, Sara M. Volk, Dana L. Vanlandingham, Scott C. Weaver, Stephen Higgs

published 31 Aug 2009

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Effects of Point Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropterate Synthase Genes on Clinical Outcomes and In Vitro Susceptibility to Sulfadoxine and Pyrimethamine

David J. Bacon, Doug Tang, Carola Salas, Norma Roncal, Carmen Lucas, Lucia Gerena, Lorena Tapia, A. Alejandro Llanos-Cuentas, Coralith Garcia, Lelv Solari, Dennis Kyle, Alan J. Magill

published 26 Aug 2009

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Identification of a Domain which Affects Kinetics and Antagonistic Potency of Clozapine at 5-HT₃ Receptors

Gerhard Rammes, Christine Hosp, Brigitte Eisensamer, Sascha Tanasic, Caroline Nothdurfter, Walter Zieglgänsberger, Rainer Rupprecht

published 21 Aug 2009

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Loss of Anti-Bax Function in Gerstmann-Sträussler-Scheinker Syndrome-Associated Prion Protein Mutants

Julie Jodoin, Micheal Misiewicz, Priya Makhijani, Paresa N. Giannopoulos, Jennifer Hammond, Cynthia G. Goodyer, Andréa C. LeBlanc

published 14 Aug 2009

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Multisite Phosphorylation of the Guanine Nucleotide Exchange Factor Cdc24 during Yeast Cell Polarization

Stephanie C. Wai, Scott A. Gerber, Rong Li

published 10 Aug 2009

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