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Point mutation

The Background of Mitochondrial DNA Haplogroup J Increases the Sensitivity of Leber's Hereditary Optic Neuropathy Cells to 2,5-Hexanedione Toxicity

Anna Ghelli, Anna Maria Porcelli, Claudia Zanna, Sara Vidoni, Stefano Mattioli, Anna Barbieri, Luisa Iommarini, Maria Pala, Alessandro Achilli, Antonio Torroni, Michela Rugolo, Valerio Carelli

published 19 Nov 2009

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High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic Leukemia

María Cerezo, Hans-Jürgen Bandelt, Idoia Martín-Guerrero, Maite Ardanaz, Ana Vega, Ángel Carracedo, África García-Orad, Antonio Salas

published 18 Nov 2009

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Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

Laura E. MacConaill, Catarina D. Campbell, Sarah M. Kehoe, Adam J. Bass, Charles Hatton, Lili Niu, Matt Davis, Keluo Yao, Megan Hanna, Chandrani Mondal, Lauren Luongo, Caroline M. Emery, Alissa C. Baker, Juliet Philips, Deborah J. Goff, Michelangelo Fiorentino, Mark A. Rubin, Kornelia Polyak, Jennifer Chan, Yuexiang Wang, Jonathan A. Fletcher, Sandro Santagata, Gianni Corso, Franco Roviello, Ramesh Shivdasani, Mark W. Kieran, Keith L. Ligon, Charles D. Stiles, William C. Hahn, Matthew L. Meyerson, Levi A. Garraway

published 18 Nov 2009

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Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein

Gallen B. Triana-Baltzer, Larisa V. Gubareva, Alexander I. Klimov, David F. Wurtman, Ronald B. Moss, Maria Hedlund, Jeffrey L. Larson, Robert B. Belshe, Fang Fang

published 06 Nov 2009

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Targeted KRAS Mutation Assessment on Patient Tumor Histologic Material in Real Time Diagnostics

Vassiliki Kotoula, Elpida Charalambous, Bart Biesmans, Andigoni Malousi, Eleni Vrettou, George Fountzilas, George Karkavelas

published 04 Nov 2009

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Screening for Microsatellite Instability Identifies Frequent 3′-Untranslated Region Mutation of the RB1-Inducible Coiled-Coil 1 Gene in Colon Tumors

Bogdan C. Paun, Yulan Cheng, Barbara A. Leggett, Joanne Young, Stephen J. Meltzer, Yuriko Mori

published 02 Nov 2009

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Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block

Franck C. Chatelain, Sabrina Gazzarrini, Yuichiro Fujiwara, Cristina Arrigoni, Courtney Domigan, Giuseppina Ferrara, Carlos Pantoja, Gerhard Thiel, Anna Moroni, Daniel L. Minor Jr.

published 16 Oct 2009

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Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Anshuman Dixit, Lin Yi, Ragul Gowthaman, Ali Torkamani, Nicholas J. Schork, Gennady M. Verkhivker

published 16 Oct 2009

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An Enhanced Single Base Extension Technique for the Analysis of Complex Viral Populations

Dale R. Webster, Armin G. Hekele, Adam S. Lauring, Kael F. Fischer, Hao Li, Raul Andino, Joseph L. DeRisi

published 16 Oct 2009

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Point Mutations in GLI3 Lead to Misregulation of its Subcellular Localization

Sybille Krauß, Joyce So, Melanie Hambrock, Andrea Köhler, Melanie Kunath, Constance Scharff, Martina Wessling, Karl-Heinz Grzeschik, Rainer Schneider, Susann Schweiger

published 15 Oct 2009

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Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer

Andrea Sartore-Bianchi, Federica Di Nicolantonio, Michele Nichelatti, Francesca Molinari, Sara De Dosso, Piercarlo Saletti, Miriam Martini, Tiziana Cipani, Giovanna Marrapese, Luca Mazzucchelli, Simona Lamba, Silvio Veronese, Milo Frattini, Alberto Bardelli, Salvatore Siena

published 02 Oct 2009

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BtubA-BtubB Heterodimer Is an Essential Intermediate in Protofilament Assembly

Christopher A. Sontag, Harvey Sage, Harold P. Erickson

published 29 Sep 2009

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Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes

Konstantin A. Tsetsarkin, Charles E. McGee, Sara M. Volk, Dana L. Vanlandingham, Scott C. Weaver, Stephen Higgs

published 31 Aug 2009

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