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Point mutation

Cancer Cells Acquire Mitotic Drug Resistance Properties Through Beta I-Tubulin Mutations and Alterations in the Expression of Beta-Tubulin Isotypes

Chun Hei Antonio Cheung, Su-Ying Wu, Tian-Ren Lee, Chi-Yen Chang, Jian-Sung Wu, Hsing-Pang Hsieh, Jang-Yang Chang

published 03 Sep 2010

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Structural and Mutational Analysis of Functional Differentiation between Synaptotagmins-1 and -7

Mingshan Xue, Timothy K. Craig, Ok-Ho Shin, Liyi Li, Chad A. Brautigam, Diana R. Tomchick, Thomas C. Südhof, Christian Rosenmund, Josep Rizo

published 02 Sep 2010

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Rapid Identification of Genetic Modifications in Bacillus anthracis Using Whole Genome Draft Sequences Generated by 454 Pyrosequencing

Peter E. Chen, Kristin M. Willner, Amy Butani, Shakia Dorsey, Matroner George, Andrew Stewart, Shannon M. Lentz, Christopher E. Cook, Arya Akmal, Lance B. Price, Paul S. Keim, Alfred Mateczun, Trupti N. Brahmbhatt, Kimberly A. Bishop-Lilly, Michael E. Zwick, Timothy D. Read, Shanmuga Sozhamannan

published 25 Aug 2010

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Glycosaminoglycan Sulphation Affects the Seeded Misfolding of a Mutant Prion Protein

Victoria A. Lawson, Brooke Lumicisi, Jeremy Welton, Dorothy Machalek, Katrina Gouramanis, Helen M. Klemm, James D. Stewart, Colin L. Masters, David E. Hoke, Steven J. Collins, Andrew F. Hill

published 23 Aug 2010

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Optimizing Combination Therapies with Existing and Future CML Drugs

Allen A. Katouli, Natalia L. Komarova

published 23 Aug 2010

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JAK2 Exon 14 Deletion in Patients with Chronic Myeloproliferative Neoplasms

Wanlong Ma, Hagop Kantarjian, Xi Zhang, Xiuqiang Wang, Zhong Zhang, Chen-Hsiung Yeh, Susan O'Brien, Francis Giles, Jean Marie Bruey, Maher Albitar

published 13 Aug 2010

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sel-11 and cdc-42, Two Negative Modulators of LIN-12/Notch Activity in C. elegans

Min Sung Choi, Andrew S. Yoo, Iva Greenwald

published 29 Jul 2010

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Population Genetics of Streptococcus dysgalactiae Subspecies equisimilis Reveals Widely Dispersed Clones and Extensive Recombination

David J. McMillan, Debra E. Bessen, Marcos Pinho, Candace Ford, Gerod S. Hall, José Melo-Cristino, Mário Ramirez

published 23 Jul 2010

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NMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural Features

Gregor Ilc, Gabriele Giachin, Mariusz Jaremko, Łukasz Jaremko, Federico Benetti, Janez Plavec, Igor Zhukov, Giuseppe Legname

published 22 Jul 2010

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Identification of the Rheumatoid Arthritis Shared Epitope Binding Site on Calreticulin

Song Ling, Andrew Cheng, Paul Pumpens, Marek Michalak, Joseph Holoshitz

published 22 Jul 2010

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Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

Asimina Hiona, Alberto Sanz, Gregory C. Kujoth, Reinald Pamplona, Arnold Y. Seo, Tim Hofer, Shinichi Someya, Takuya Miyakawa, Chie Nakayama, Alejandro K. Samhan-Arias, Stephane Servais, Jamie L. Barger, Manuel Portero-Otín, Masaru Tanokura, Tomas A. Prolla, Christiaan Leeuwenburgh

published 07 Jul 2010

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An Induced Mutation in Tomato eIF4E Leads to Immunity to Two Potyviruses

Florence Piron, Maryse Nicolaï, Silvia Minoïa, Elodie Piednoir, André Moretti, Aurélie Salgues, Dani Zamir, Carole Caranta, Abdelhafid Bendahmane

published 25 Jun 2010

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JAK2 V617F Constitutive Activation Requires JH2 Residue F595: A Pseudokinase Domain Target for Specific Inhibitors

Alexandra Dusa, Céline Mouton, Christian Pecquet, Murielle Herman, Stefan N. Constantinescu

published 16 Jun 2010

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