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Plasma cell disorders

Anti-Myeloma Activity of Akt Inhibition Is Linked to the Activation Status of PI3K/Akt and MEK/ERK Pathway

Vijay Ramakrishnan, Teresa Kimlinger, Jessica Haug, Utkarsh Painuly, Linda Wellik, Timothy Halling, S. Vincent Rajkumar, Shaji Kumar

published 21 Nov 2012

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Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells

Junling Zhuang, Jianghong Zhang, Seint T. Lwin, James R. Edwards, Claire M. Edwards, Gregory R. Mundy, Xiangli Yang

published 16 Nov 2012

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Functionally Suppressive CD8 T Regulatory Cells Are Increased in Patients with Multiple Myeloma: A Cause for Immune Impairment

Karthick Raja Muthu Raja, Lenka Kubiczkova, Lucie Rihova, Martin Piskacek, Pavla Vsianska, Renata Hezova, Ludek Pour, Roman Hajek

published 13 Nov 2012

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Inhibition of BDNF in Multiple Myeloma Blocks Osteoclastogenesis via Down-Regulated Stroma-Derived RANKL Expression Both In Vitro and In Vivo

Li-Sha Ai, Chun-Yan Sun, Lu Zhang, Shun-Chang Zhou, Zhang-Bo Chu, You Qin, Ya-Dan Wang, Wei Zeng, Han Yan, Tao Guo, Lei Chen, Di Yang, Yu Hu

published 15 Oct 2012

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Increased T Regulatory Cells Are Associated with Adverse Clinical Features and Predict Progression in Multiple Myeloma

Karthick Raja Muthu Raja, Lucie Rihova, Lenka Zahradova, Maria Klincova, Miroslav Penka, Roman Hajek

published 10 Oct 2012

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In Silico Investigations of the Anti-Catabolic Effects of Pamidronate and Denosumab on Multiple Myeloma-Induced Bone Disease

Yan Wang, Bo Lin

published 21 Sep 2012

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An Anilinoquinazoline Derivative Inhibits Tumor Growth through Interaction with hCAP-G2, a Subunit of Condensin II

Hirokazu Shiheido, Yuhei Naito, Hironobu Kimura, Hiroaki Genma, Hideaki Takashima, Mayuko Tokunaga, Takao Ono, Tatsuya Hirano, Wenlin Du, Taketo Yamada, Nobuhide Doi, Shiro Iijima, Yutaka Hattori, Hiroshi Yanagawa

published 13 Sep 2012

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Soluble Rank Ligand Produced by Myeloma Cells Causes Generalised Bone Loss in Multiple Myeloma

Clive Henry Buckle, Evy De Leenheer, Michelle Anne Lawson, Kwee Yong, Neil Rabin, Mark Perry, Karen Vanderkerken, Peter Ian Croucher

published 29 Aug 2012

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Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10-Producing Regulatory B Cells and High BAFF Levels

Anne Saussine, Abdellatif Tazi, Séverine Feuillet, Michel Rybojad, Caroline Juillard, Anne Bergeron, Valérie Dessirier, Fatiha Bouhidel, Anne Janin, Armand Bensussan, Martine Bagot, Jean-David Bouaziz

published 22 Aug 2012

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Virotherapy Using Myxoma Virus Prevents Lethal Graft-versus-Host Disease following Xeno-Transplantation with Primary Human Hematopoietic Stem Cells

Eric Bartee, Amy Meacham, Elizabeth Wise, Christopher R. Cogle, Grant McFadden

published 14 Aug 2012

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miRSystem: An Integrated System for Characterizing Enriched Functions and Pathways of MicroRNA Targets

Tzu-Pin Lu, Chien-Yueh Lee, Mong-Hsun Tsai, Yu-Chiao Chiu, Chuhsing Kate Hsiao, Liang-Chuan Lai, Eric Y. Chuang

published 01 Aug 2012

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Identification of Pluripotent and Adult Stem Cell Genes Unrelated to Cell Cycle and Associated with Poor Prognosis in Multiple Myeloma

Alboukadel Kassambara, Dirk Hose, Jérôme Moreaux, Thierry Rème, Jennifer Torrent, Jean François Rossi, Hartmut Goldschmidt, Bernard Klein

published 31 Jul 2012

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Integrative Gene Expression Profiling Reveals G6PD-Mediated Resistance to RNA-Directed Nucleoside Analogues in B-Cell Neoplasms

Samuel K. McBrayer, Michael Yarrington, Jun Qian, Gang Feng, Mala Shanmugam, Varsha Gandhi, Nancy L. Krett, Steven T. Rosen

published 27 Jul 2012

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