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Pharmacologic analysis

Novel Linalool-Silver nanoparticles: Synthesis, characterization, and dual approach evaluation via computational docking and antibacterial assays

Hina Manzoor, Mohammad A. Alfhili, Shakeel Waqqar, Malik Arslan Ali, Faiza Hassan, Samiullah Khan, Muhammad Umer Khan

published 28 Oct 2025

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Pharmacokinetic profile of oral firocoxib in the koala (Phascolarctos cinereus)

Amanda June Shapiro, Benjamin Kimble, Frances Hulst, Kimberly Vinette Herrin, Caroline Marschner, Chien-Jung Chen, Merran Govendir

published 30 Sep 2025

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Determining minimal inhibitory concentrations and antibiotic susceptibility for Enterobacterales by flow cytometry using reactive oxygen species as a marker

Jia Hao Yeo, Nasren Begam, Wan Ting Leow, Andrea Lay-Hoon Kwa

published 04 Sep 2025

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Investigation of carbapenemase-encoding genes in Burkholderia cepacia and Aeromonas sobria isolates from nosocomial infections in Iraqi patients

Mushtak T. S. Al-Ouqaili, Rawaa A. Hussein, Bushra A. Kanaan, Ahmed T. S. Al-Neda

published 29 Aug 2025

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Clindamycin-resistant among Staphylococcus aureus: Investigation into phenotypic and genotypic profiles

Mariyam Khursheed, Maryam Sulaiman, Abdulrahman M. Alhassan, Tameem H. Al Awad, Ahmed E. Ibrahim, Godwin Wilson, Hana A. Abdelrahaman, Nahla O. Eltai

published 18 Aug 2025

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CRISPR-Cas9 targeting the bla_KPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants

Thaysa Leite Tagliaferri, Alex Krüttgen, Tiago Antônio de Oliveira Mendes, Simone Gonçalves dos Santos, Hans-Peter Horz

published 12 Aug 2025

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Unraveling the global landscape of Elizabethkingia antibiotic resistance: A systematic review and meta-analysis

Saade Abdalkareem Jasim, Jaafaru Sani Mohammed, Rangaswamy Roopashree, Mohammad Y. Alshahrani, Aanchal Sharma, Abhishek Sharma, Shodiyev Asliddin, Masoumeh Beig

published 30 May 2025

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Antimicrobial-resistance of Escherichia coli in dogs and cats: A scoping review

Rasaq A. Ojasanya, J. Scott Weese, Zvonimir Poljak, Kurtis E. Sobkowich, Uththami Kukathasan, Theresa M. Bernardo

published 30 May 2025

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Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial

Niklas Walther, Robert Schultz-Heienbrok, Heino Staß, Victor M. Corman, Nils C. Gassen, Marcel A. Müller, Christian Drosten, Martin Witzenrath, Hweeling Lee, Maximilian G. Posch

published 25 Feb 2025

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Platinum retention in plasma, urine, and normal colonic mucosa in cisplatin-treated testicular cancer survivors

Emilie C. H. Breekveldt, Berbel L. M. Ykema, Alwin D. R. Huitema, Jourik A. Gietema, Jos H. Beijnen, Petur Snaebjornsson, Michael Schaapveld, Flora E. van Leeuwen, Hilde Rosing, Monique E. van Leerdam, on behalf of the CATCHER study working group

published 14 Nov 2024

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Pembrolizumab 400 mg every 6 weeks as first-line therapy for advanced melanoma (KEYNOTE-555): Results from cohort B of an open-label, phase 1 study

Graham Cohen, Bernardo Rapoport, Sze W. Chan, Paul Ruff, Ana Arance, Karmele Mujika Eizmendi, Baerin Houghton, Michael P. Brown, Robert M. Zielinski, Eva Muñoz Couselo, Megan Lyle, James R. Anderson, Lokesh Jain, Dinesh de Alwis, Mallika Lala, Omobolaji Akala, Elliot Chartash, Conrad Jacobs

published 12 Nov 2024

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Prolonging the circulatory half-life of C1 esterase inhibitor via albumin fusion

Sangavi Sivananthan, Varsha Bhakta, Negin Chaechi Tehrani, William P. Sheffield

published 23 Oct 2024

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In vivo pharmacokinetics of ginsenoside compound K mediated by gut microbiota

Ming-Si Deng, Su-tian-zi Huang, Ya-Ni Xu, Li Shao, Zheng-Guang Wang, Liang-Jian Chen, Wei-Hua Huang

published 23 Aug 2024

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