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Pharmacologic analysis

New Delhi Metallo-β-Lactamase 1(NDM-1), the Dominant Carbapenemase Detected in Carbapenem-Resistant Enterobacter cloacae from Henan Province, China

Cailin Liu, Shangshang Qin, Hui Xu, Lijuan Xu, Di Zhao, Xuchun Liu, Shaolei Lang, Xianju Feng, Hong-Min Liu

published 11 Aug 2015

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Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase

David G. Warnock, Daniel G. Bichet, Myrl Holida, Ozlem Goker-Alpan, Kathy Nicholls, Mark Thomas, Francois Eyskens, Suma Shankar, Mathews Adera, Sheela Sitaraman, Richie Khanna, John J. Flanagan, Brandon A. Wustman, Jay Barth, Carrolee Barlow, Kenneth J. Valenzano, David J. Lockhart, Pol Boudes, Franklin K. Johnson

published 07 Aug 2015

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Degradation and Stabilization of Peptide Hormones in Human Blood Specimens

Jizu Yi, David Warunek, David Craft

published 29 Jul 2015

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Comparative Pharmacokinetics and Allometric Scaling of Carboplatin in Different Avian Species

Gunther Antonissen, Mathias Devreese, Siegrid De Baere, Tom Hellebuyck, Isabel Van de Maele, Lieze Rouffaer, Hendrickus J. J. Stemkens, Patrick De Backer, An Martel, Siska Croubels

published 29 Jul 2015

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Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

James E. Korkola, Eric A. Collisson, Laura Heiser, Chris Oates, Nora Bayani, Sleiman Itani, Amanda Esch, Wallace Thompson, Obi L. Griffith, Nicholas J. Wang, Wen-Lin Kuo, Brian Cooper, Jessica Billig, Safiyyah Ziyad, Jenny L. Hung, Lakshmi Jakkula, Heidi Feiler, Yiling Lu, Gordon B. Mills, Paul T. Spellman, Claire Tomlin, Sach Mukherjee, Joe W. Gray

published 16 Jul 2015

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Potentiation of Growth Inhibitory Responses of the mTOR Inhibitor Everolimus by Dual mTORC1/2 Inhibitors in Cultured Breast Cancer Cell Lines

Euphemia Y. Leung, Marjan Askarian-Amiri, Graeme J. Finlay, Gordon W. Rewcastle, Bruce C. Baguley

published 06 Jul 2015

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Enhanced Lacto-Tri-Peptide Bio-Availability by Co-Ingestion of Macronutrients

Gabriella A. M. Ten Have, Pieter C. van der Pijl, Arie K. Kies, Nicolaas E. P. Deutz

published 22 Jun 2015

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Aminobacter MSH1-Mineralisation of BAM in Sand-Filters Depends on Biological Diversity

Flemming Ekelund, Christoffer Bugge Harder, Berith Elkær Knudsen, Jens Aamand

published 15 Jun 2015

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Three Dimensional Checkerboard Synergy Analysis of Colistin, Meropenem, Tigecycline against Multidrug-Resistant Clinical Klebsiella pneumonia Isolates

Claudia Stein, Oliwia Makarewicz, Jürgen A. Bohnert, Yvonne Pfeifer, Miriam Kesselmeier, Stefan Hagel, Mathias W. Pletz

published 11 Jun 2015

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Validation of Perfusion Quantification with 3D Gradient Echo Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using a Blood Pool Contrast Agent in Skeletal Swine Muscle

Stefan Hindel, Anika Sauerbrey, Marc Maaß, Stefan Maderwald, Marc Schlamann, Lutz Lüdemann

published 10 Jun 2015

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Pharmacokinetics of Novel Plant Cell-Expressed Taliglucerase Alfa in Adult and Pediatric Patients with Gaucher Disease

Richat Abbas, Glen Park, Bharat Damle, Raul Chertkoff, Sari Alon

published 08 Jun 2015

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Amino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in Rats

Federica Vacondio, Michele Bassi, Claudia Silva, Riccardo Castelli, Caterina Carmi, Laura Scalvini, Alessio Lodola, Valentina Vivo, Lisa Flammini, Elisabetta Barocelli, Marco Mor, Silvia Rivara

published 08 Jun 2015

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Preclinical Pharmacokinetic Studies of the Tritium Labelled D-Enantiomeric Peptide D3 Developed for the Treatment of Alzheimer´s Disease

Nan Jiang, Leonie H. E. Leithold, Julia Post, Tamar Ziehm, Jörg Mauler, Lothar Gremer, Markus Cremer, Elena Schartmann, N. Jon Shah, Janine Kutzsche, Karl-Josef Langen, Jörg Breitkreutz, Dieter Willbold, Antje Willuweit

published 05 Jun 2015

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