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Pharmacodynamics

NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease

Joshua J. Field, Elaine Majerus, [ ... ], David G. Nathan

Efficacy and Safety of Once-Daily Insulin Degludec/Insulin Aspart versus Insulin Glargine (U100) for 52 Weeks in Insulin-Naïve Patients with Type 2 Diabetes: A Randomized Controlled Trial

Ajay Kumar, Edward Franek, [ ... ], Rafael Simó

Pharmacodynamic Impact of Carboxylesterase 1 Gene Variants in Patients with Congestive Heart Failure Treated with Angiotensin-Converting Enzyme Inhibitors

Karl Emil Nelveg-Kristensen, Peter Bie, [ ... ], INDICES Consortium

Defining the Active Fraction of Daptomycin against Methicillin-Resistant Staphylococcus aureus (MRSA) Using a Pharmacokinetic and Pharmacodynamic Approach

Samira M. Garonzik, Justin R. Lenhard, [ ... ], Brian T. Tsuji

Pharmacokinetic-Pharmacodynamic Analysis on Inflammation Rat Model after Oral Administration of Huang Lian Jie Du Decoction

Wei Ren, Ran Zuo, [ ... ], Nan Si

Impact on Bacterial Resistance of Therapeutically Nonequivalent Generics: The Case of Piperacillin-Tazobactam

Carlos A. Rodriguez, Maria Agudelo, [ ... ], Omar Vesga

Clinical Validation of Therapeutic Drug Monitoring of Imipenem in Spent Effluent in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Pilot Study

Aiping Wen, Zhe Li, [ ... ], Jing Bai

The qEEG Signature of Selective NMDA NR2B Negative Allosteric Modulators; A Potential Translational Biomarker for Drug Development

Deborah Keavy, Linda J. Bristow, [ ... ], Michael R. Weed

MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses

Adam D. Bachstetter, Zhengqiu Zhou, [ ... ], Linda J. Van Eldik

A Randomized Trial of Pharmacogenetic Warfarin Dosing in Naïve Patients with Non-Valvular Atrial Fibrillation

Vittorio Pengo, Carlo-Federico Zambon, [ ... ], Mario Plebani

Demonstration of Therapeutic Equivalence of Fluconazole Generic Products in the Neutropenic Mouse Model of Disseminated Candidiasis

Javier M. Gonzalez, Carlos A. Rodriguez, [ ... ], Omar Vesga

Determination of the Optimal Concentration of Valproic Acid in Patients with Epilepsy: A Population Pharmacokinetic-Pharmacodynamic Analysis

Hiroo Nakashima, Kentaro Oniki, [ ... ], Junji Saruwatari

Single and Multiple Dose Pharmacokinetics, Pharmacodynamics and Safety of the Novel Lipoprotein-Associated Phospholipase A₂ Enzyme Inhibitor Darapladib in Healthy Chinese Subjects: An Open Label Phase-1 Clinical Trial

Chaoying Hu, Debra Tompson, [ ... ], Yun Liu

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