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Pharmaceutics

Computational repurposing of approved drugs targeting KRAS G12D and EGFR for colorectal cancer therapy

Walaa Ibraheem, Fatima Alsheikh, Abdulrahim A. Alzain, Bhoomendra A. Bhongade, Laila Ejaz, Hamnah Baig, Robert C. Robinson, Mohamed El-Tanani

published 28 Jan 2026

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S100-alarmins, antenatal corticosteroids and the risk of late-onset sepsis in preterm infants: A prospective cohort study

Gloria Kessler, Thomas Ulas, Thomas Vogl, Johannes Roth, Fenja Albrecht, Gesine Hansen, Constantin S. von Kaisenberg, Christoph Härtel, Bettina Bohnhorst, Dorothee Viemann, Sabine Pirr

published 27 Jan 2026

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Adult airway management in ICU and regular floors: A prospective study as part of a healthcare improvement initiative in a tertiary care center

Carine Zeeni, Mohamed Al Jazzar, Wissam Maroun, Thuraya HajAli, Marc Moukarzel, Rawad Jamaleddine, Patrick Maroun, Marie T. Aouad

published 27 Jan 2026

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Postoperative swallowing recovery in oral and oropharyngeal cancer: A prospective analysis of functional changes and adjuvant therapy effects

Loan Thi Hong Nguyen, Duc Tan Vo, Truc Thanh Thai, Xuan Quang Ly

published 27 Jan 2026

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Effect of esketamine-based patient-controlled intravenous analgesia on postoperative pain and quality of recovery after video-assisted thoracoscopic lobectomy: A prospective, double-blind, randomized controlled trial

Ruirui Bi, Jiqiang Zhang, Ruijuan Liu, Lijuan Li, Yuxi Su, Mengjun Xu, Wenjun Yan

published 27 Jan 2026

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Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights

Ana Paula da Silva Pinheiro, Glaucia Vilar-Pereira, Leda Castaño-Barrios, Isalira Peroba Rezende Ramos, Yasmin Pedra-Rezende, Luiza Dantas-Pereira, Rubem Figueiredo Sadok Menna-Barreto, Daniel Gibaldi, Hilton Antônio Mata-Santos, Joseli Lannes-Vieira

published 27 Jan 2026

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Exploring innovative G-CSF schedules in AML cytarabine-based consolidation through a digital twin study of white blood cell recovery

Adrian-Manuel Reimann, Enrico Schalk, Dimitrios Mougiakakos, Thomas Fischer, Sebastian Sager

published 27 Jan 2026

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Cardiovascular risk among middle-aged Japanese adults with atopic dermatitis: A nested case–control study

Misato Maeno, Mami Ishida, Risa Tamagawa-Mineoka, Naoyuki Takashima, Hiroshi Ikai

published 23 Jan 2026

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Pharmacokinetics of Dolutegravir, nucleoside analogues, and intracellular metabolites using plasma separation cards: A comparative analysis with traditional sampling methods in healthy volunteers

Beth Thompson, Laura J. Else, Laura Dickinson, Stacey Edick, Ashley Zyhowski, Ken Ho, Leslie Meyn, Sujan Dilly-Penchala, Victoria Shaw, Ian McGowan, Saye Khoo, Rhonda M. Brand

published 23 Jan 2026

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Clinical proof of concept for small molecule mediated inhibition of IL-17 in psoriasis

Richard B. Warren, Hamish J. A. Hunter, Kim A. Papp, Kenneth B. Gordon, Meina T. Tang, Jeffrey V. Enejosa, Kuan-Chieh Huang, Debasish Raha, Hashini M. Batugedara, Craig Skinner, Philip A. Kobel, Peter M. Rademacher, Nico Ghilardi, Paul Fatheree, John R. Jacobsen, Timothy T. Lu

published 23 Jan 2026

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Bio-waste derived fluorescent carbon dots based biodegradable mechanically strong hydrogel for stimuli-responsive nonsteroidal anti-inflammatory drug (NSAID) delivery

Sina M. Matalqah, Venkata Ramana Singamaneni, Patibandla Jahnavi, Umme Hani, Farhat Fatima, Rajeshwar Vodeti, Prem Shankar Gupta, Mohammad Badrud Duza, Md. Al Amin

published 23 Jan 2026

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Clinical characteristics, diagnostic modalities, and therapeutic strategies of spontaneous renal artery dissection: A systematic review and diagnostic analysis

Jiahao Zhu, Zengqiang Xu, Yang Geng, Mengxin Jiang, Chang Xu, Yingjiang Xu

published 23 Jan 2026

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Single-cell RNA-seq reveals the piperlongumine is a potential drug for ischemic stroke

Jinwei Li, Xiaosi Zhu, Yan Zhang, Zixia Xu, Yurui Zhuang, Liqi Chen, Yan Cao, Chuan Chang, Yao Lv

published 23 Jan 2026

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