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Pharmaceutical processing technology

First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1

Kathryn E. Stephenson, Michael C. Keefer, Catherine A. Bunce, Doreen Frances, Peter Abbink, Lori F. Maxfield, George H. Neubauer, Joseph Nkolola, Lauren Peter, Christopher Lane, Harriet Park, Carl Verlinde, Angela Lombardo, Christopher Yallop, Menzo Havenga, Patricia Fast, John Treanor, Dan H. Barouch

published 14 Nov 2018

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Characterization of immunogenicity of avian influenza antigens encapsulated in PLGA nanoparticles following mucosal and subcutaneous delivery in chickens

Tamiru Negash Alkie, Alexander Yitbarek, Khaled Taha-Abdelaziz, Jake Astill, Shayan Sharif

published 01 Nov 2018

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Preparation of acacia tannin loaded lipid microparticles by solid-in-oil-in-water and melt dispersion methods, their characterization and evaluation of their effect on ruminal gas production In Vitro

Festus A. Adejoro, Abubeker Hassen, Mapitsi S. Thantsha

published 25 Oct 2018

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Comparative analysis of different preservation techniques for the storage of Staphylococcus phages aimed for the industrial development of phage-based antimicrobial products

Eva González-Menéndez, Lucía Fernández, Diana Gutiérrez, Ana Rodríguez, Beatriz Martínez, Pilar García

published 11 Oct 2018

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Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles

Adam O. Whelan, Helen C. Flick-Smith, Jane Homan, Zu T. Shen, Zoe Carpenter, Payam Khoshkenar, Ambily Abraham, Nicola J. Walker, Stuart M. Levitz, Gary R. Ostroff, Petra C. F. Oyston

published 08 Oct 2018

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Optimization of the Cohesion Index in the SeDeM Diagram Expert System and application of SeDeM Diagram: An improved methodology to determine the Cohesion Index

Isaac Nofrerias, Anna Nardi, Marc Suñé-Pou, Joost Boeckmans, Josep Maria Suñé-Negre, Encarna García-Montoya, Pilar Pérez-Lozano, Josep Ramón Ticó-Grau, Montserrat Miñarro-Carmona

published 13 Sep 2018

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Development of a broad spectrum glycoconjugate vaccine to prevent wound and disseminated infections with Klebsiella pneumoniae and Pseudomonas aeruginosa

Nicolas Hegerle, Myeongjin Choi, James Sinclair, Mohammed N. Amin, Morgane Ollivault-Shiflett, Brittany Curtis, Rachel S. Laufer, Surekha Shridhar, Jerod Brammer, Franklin R. Toapanta, Ian Alan Holder, Marcela F. Pasetti, Andrew Lees, Sharon M. Tennant, Alan S. Cross, Raphael Simon

published 06 Sep 2018

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Identifying genetic diversity of O antigens in Aeromonas hydrophila for molecular serotype detection

Hengchun Cao, Min Wang, Qian Wang, Tingting Xu, Yuhui Du, Huiying Li, Chengqian Qian, Zhiqiu Yin, Lu Wang, Yi Wei, Pan Wu, Xi Guo, Bin Yang, Bin Liu

published 05 Sep 2018

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Characterization of natural bactericidal antibody against Haemophilus influenzae type a in Canadian First Nations: A Canadian Immunization Research Network (CIRN) Clinical Trials Network (CTN) study

Eli B. Nix, Joshua Choi, Christina Anthes, Gabrielle N. Gaultier, Joelle Thorgrimson, Andrew D. Cox, Raymond S. W. Tsang, William G. McCready, Douglas Boreham, Marina Ulanova

published 15 Aug 2018

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Effect of microencapsulated essential oil form Chamaecyparis obtusa on monocyte-derived dendritic cell activation and CD4⁺ T cell polarization

Seung-Heon Shin, Mi-Kyung Ye, Dong-Won Lee, Mi-Hyun Che

published 27 Jul 2018

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Galactose-1-phosphate uridyltransferase (GalT), an in vivo-induced antigen of Actinobacillus pleuropneumoniae serovar 5b strain L20, provided immunoprotection against serovar 1 strain MS71

Fei Zhang, Qin Zhao, Keji Quan, Zhuang Zhu, Yusheng Yang, Xintian Wen, Yung-Fu Chang, Xiaobo Huang, Rui Wu, Yiping Wen, Qigui Yan, Yong Huang, Xiaoping Ma, Xinfeng Han, Sanjie Cao

published 01 Jun 2018

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Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy

Petr O. Ilyinskii, Grigoriy I. Kovalev, Conlin P. O’Neil, Christopher J. Roy, Alicia M. Michaud, Natalia M. Drefs, Mikhail A. Pechenkin, Fen-ni Fu, Lloyd P. M. Johnston, Dmitry A. Ovchinnikov, Takashi Kei Kishimoto

published 01 Jun 2018

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A multi-level model of emerging technology: An empirical study of the evolution of biotechnology from 1976 to 2003

Ad van den Oord, Arjen van Witteloostuijn

published 24 May 2018

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