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Pathogenesis

Single cell RNA sequencing analysis and molecular biology experiments identify NAFLD-related fibroblasts and highlights seven hub genes in NAFLD

Xuechun Zhang, Ying Cheng, Runzhi Yu, Xiaona Hu, Yiqin Huang

published 02 Feb 2026

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Transcriptional regulator NtrC modulates nitrogen assimilation, virulence, and the extracellular glutamine synthetase activity in Acinetobacter baumannii

Akram J. Alahmar, Noha M. Elhosseiny, Rehab R. Mahmoud, Ahmed S. Attia

published 23 Jan 2026

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Machine learning and network pharmacology identify keloid biomarkers (AMPH, TNFRSF9) and therapeutic targets (IL6, HAS2) for aloe-derived quercetin

Congli Jia, Fu Yang, Yingchun Li

published 16 Jan 2026

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Genetic analysis of LRRK2 variants in Han Chinese patients with Parkinson’s disease

Xinyue Deng, Xue Yan, Zhi Song, Wen Zheng, Hongbo Xu, Yan Yang, Jiangang Wang, Lamei Yuan, Hao Deng

published 08 Jan 2026

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Mechanistic study of plastic monomers in gestational diabetes mellitus: A network toxicology and molecular docking approach

Yingying Feng, Tingting Huang

published 29 Dec 2025

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Isolation and characterization of the phytopathogenic fungus Ilyonectria liriodendri from persimmon as a new susceptible host

Nikolett Molnár, Dóra Szabó, Adrienn Geiger, József Geml, Kálmán Zoltán Váczy, Zoltán Karácsony

published 26 Dec 2025

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Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease

Yohan David Soreze, Tifenn Desroziers-Louedec, Aurore Carré, Farah Diab, Aphrodite Daskalopoulou, Julie Starck, Valérie Nau, Marie Legendre, Sonia-Athina Karabina, Véronique Houdouin, Aurore Coulomb-L’herminé, Camille Louvrier, Nadia Nathan

published 19 Dec 2025

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Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis

Lei Guo, Jun Ge, Li Cheng, Xinyi Zhang, Zhengzheng Wu, Meili Liu, Hanmei Jiang, Wei Gong, Yi Liu

published 17 Dec 2025

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Integrated multi-omics analysis reveals necroptosis-related biomarker BIRC3 for early diagnosis and therapeutic targeting in preeclampsia

Qingxia Lin, Peifeng Huang, Youhong Kang, Yanfeng Lu, Guili Shi

published 01 Dec 2025

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Parasites of the hermit crab Pagurus hirsutiusculus; distribution, prevalence, and thermal ecology

Madeleine H. Abbott, Christopher D.G. Harley, Harmony A. Martell, Carly Janusson, Matthew A. Lemay, Alyssa-Lois M. Gehman

published 19 Nov 2025

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Unveiling and verification of mitochondria-related genes as potential diagnostic biomarkers in ulcerative colitis based on bioinformatics analysis and experimental validation

Hongliang Chen, Ning Li, Xuerong Liu, Mingyu Ran, Xinyu Geng, Jihan Qi, Jiawei Qiu, Xueyu Cang, Shiling Huang, Yingying Tian, Ram Prasad Chaulagain, Shizhu Jin

published 04 Nov 2025

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Immuno-informatics voyage through molecular mimicry of Heat Shock Proteins: Potential IBD immunopathogenesis

Mahsa Alem, Seyyed Meysam Abtahi Froushani, Nasim Hajighahramani, Saied Hosseini-Asl, Farhad Pourfarzi, Rasoul Nemati

published 16 Oct 2025

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Machine learning-based transcriptomic analysis identifies NAMPT and SAT1 as potential biomarkers and therapeutic targets in ferroptosis-associated rheumatoid arthritis

Devi Soorya Narayana Sasikumar, Vino Sundararajan

published 29 Sep 2025

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