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Opioids

Transcranial focused ultrasound to nucleus accumbens reverses fentanyl-induced conditioned place preference in rats

Seung-Schik Yoo, Madeline S. Ewell, Evan C. Smith, Isabel L. Yu, Hyun-Chul Kim, Rajeev I. Desai

published 22 Aug 2025

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Global burden of disease due to opioid, amphetamine, cocaine, and cannabis use disorders, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021

David T. Zhu, Ye In Christopher Kwon, Alan Lai, Andrew Min–Gi Park, Andrew J. Barnes, Derek A. Chapman

published 21 Aug 2025

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Exploring the addictive processes in repetitive self-harm through a grounded theory approach: “It always felt like a choice until it didn’t”

Millie Witcher, Sarah Rowe, Sally Marlow, Jennifer Heath

published 14 Aug 2025

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Opportunistic pathogens and polycocktail drugs fuel dynamic public health threats during the opioid crisis

John H. Boman IV, Nara Souza, Jasmine Light, Dawson Holt, Shannon Jones, Angelic King, Mahjida Berryman, Sarah A. Shuda, Mia Borrelli, Barry K. Logan, Amanda L. A. Mohr, Hans Wildschutte

published 12 Aug 2025

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Cytokines interferon−γ− inducible protein 10 and granulocyte−macrophage colony−stimulating factor are associated with psychiatric symptoms in opioid−dependent patients: A cross− sectional study

Kristin Nygård−Odeh, Hedda Soløy−Nilsen, Magnhild Gangsøy−Kristiansen, Ole Lars Brekke, Tom Eirik Mollnes, Michael Berk

published 07 Aug 2025

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Relative importance of socioecological domains to predicting opioid-involved mortality

Joshua C. Black, Annika M. Czizik

published 29 Jul 2025

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Efficacy of pharmacological and non-pharmacological therapy on chronic cancer pain intensity of adults with cancer: A network meta-analysis protocol

Wenhao Su, Xueling Li, Yanru Wang

published 17 Jul 2025

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Physician perspectives on reducing harm and supporting emergency department patients who use drugs

Zoe K. D. Collins, Elaine Hyshka, Karine J. Lavergne, Savannah M. Weber, Ginetta Salvalaggio, Cindy Jiaxin Xue, Arlanna Pugh, Janusz Kaczorowski, Aaron M. Orkin, Andrew Kestler, Kathryn A. Dong

published 16 Jul 2025

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Opioid overdose and naloxone administration knowledge and perceived competency in a probability sample of Indiana urban communities with large Black populations

Shin Hyung Lee, Jon Agley, Vatsla Sharma, Francesca Williamson, Pengyue Zhang, Dong-Chul Seo

published 15 Jul 2025

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A protocol for the evaluation of the PneumoWave biosensor in supported accommodation settings: A study on feasibility and acceptability (RESCU-2)

Basak Tas, Lewis Beer, Elizabeth Appiah-Kusi, Will Lawn, Iona Belov, Polly Radcliffe, Andrew Radley, Bruce Henderson, Osian Meredith, Catriona Cowan, Stuart Kelly, Holly Maxwell Pringle, Alex Adam, John Strang, John F. Dillon

published 07 Jul 2025

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Trends of long-term opioid therapy and subsequent discontinuation among people with chronic non-cancer pain in UK primary care: A retrospective cohort study

Qian Cai, Yun-Ting Huang, Thomas Allen, Charlotte Morris, Christos Grigoroglou, Evangelos Kontopantelis

published 26 Jun 2025

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The opportunity to save a life: A qualitative study of a point-of-care overdose education and naloxone distribution intervention

Janet A Parsons, Benjamin Markowitz, Rekha Thomas, Kris Norris, Mercy Charles, Chantelle King, Kate Sellen, Douglas M Campbell, Pamela Leece, Michelle Klaiman, Leigh Chapman, Shaun Hopkins, Rita Shahin, Curtis Handford, Vicky Stergiopoulos, Laurie J. Morrison, Carol Strike, Aaron M. Orkin, on behalf of the SOONER investigators

published 25 Jun 2025

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Design, synthesis, in-vivo, and in-silico studies of 1,2,3-triazole tethered derivatives of morphine as novel anti-nociceptive agents

Faeze Nourmandipour, Reihane Emadi, Peyman Salehi, Mona Kamelan Zargar Zarin, Mona Khoramjouy, Amirreza Dowlati Beirami, Mehrdad Faizi

published 16 Jun 2025

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