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Nuclear staining

Proteomic screening of TMEM43 binding partners identifies VDAC leading to mitochondrial dysfunction

Qingqing Zhu, Guoxing Zheng, Yingsi Lu, Yizhou Jiang, Yan Li, Hong Chen, Lifen Huang, Nannan Tang, Bo Li, Yi Lu, Jian Zhang, Chengming Zhu

published 18 Dec 2025

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Matrix stiffness influences drug resistance to gemcitabine analog and AZD 1775 combination in PDAC organoids

Jonathan Barajas, Zhi Yang, Edward Agyare, Xueyou Zhu, Saun-Joo Yoon, Bo Han

published 04 Dec 2025

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PixlMap: A generalisable pixel classifier for cellular phenotyping in multiplex immunofluorescence images

Rachel L. Baird, David Mason, Kai Rakovic, Fiona Ballantyne, Ian R. Powley, Anastasia Georgakopoulou, Lucy Hillary, Thomas G. Bird, Leah Officer-Jones, John Le Quesne

published 03 Dec 2025

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Novel pyrimidine-substituted chalcones: In vitro antioxidant properties and cytotoxic effects against human cancer cell lines

Prashant Nayak, Vikram S. Shenoy, Vijay Upadhye, Kasim Sakran Abass, Omar Awad Alsaidan, Mukesh Soni, Sunil Tulshiram Hajare

published 03 Nov 2025

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Phenotypic profiling of small molecules using cell painting assay in HCT116 colorectal cancer cells

Velemir Lavrinenko, Ilona Donskaya, Vladimir Popov, Ekaterina Litau, Varvara Petrova, Stanislav Tyazhelnikov

published 29 Oct 2025

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Combined metabolomics and proteomics analysis of vascular cognitive impairment in hypertensive rats induced by endothelial injury

Xiao Zhang, Surui Chang, Jiangang Liu, Dongling Wang

published 09 Oct 2025

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A pipeline for rapid, high-throughput imaging and quantitative analysis of human intestinal organoids

Faith M. Sawyer, Fabio Stossi, Erika Nachman, Robert A. Britton, Michael J. Bolt, Michael A. Mancini, Mary K. Estes, Sarah E. Blutt

published 08 Oct 2025

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Neuronal differentiation of human dental pulp stem cells induced by co-treatment of ergothioneine

Amarin Thongsuk, Peeratchai Seemaung, Phetcharat Phanthong, Kajohnkiart Janebodin, Nisarat Ruangsawasdi, Thanasup Gonmanee, Chareerut Phruksaniyom, Tarinee Chodchavanchai, Tatcha Balit, Kenneth L. White, Charoensri Thonabulsombat, Anupong Thongklam Songsaad

published 02 Sep 2025

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Enhancing glioma immunohistochemical image classification through color deconvolution-aware prior guidance

Yiming Gao, Feiyang Niu, Hao Qin, Fang Du, Xiangmei Cao, Lijuan Song

published 02 Sep 2025

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Decellularized rat brain extracellular matrix effectively induces the dopaminergic differentiation of human adipose-derived stem cells

Hossein Faghih, Arash Javeri, Masoumeh Fakhr Taha

published 02 Sep 2025

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Correlation between neutrophil extracellular traps and macrophages in thrombi of patients with acute ischemic stroke

Mingming Zang, Ruodong Han, Xiuxia Yan

published 26 Aug 2025

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Comparison between wharton’s jelly and collagen natural hydrogels for human ovarian follicle transplantation as an artificial ovary

Farnaz Tajbakhsh, Mohammad Kazemi Ashtiani, Somayeh Tavana, Ashraf Moini, Rouhollah Fathi

published 14 Aug 2025

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Expression of human A53T alpha-synuclein without endogenous rat alpha-synuclein fails to elicit Parkinson’s disease-related phenotypes in a novel humanized rat model

Nicole K. Polinski, Jukka Puoliväli, Leena Rauhala, Taina-Kaisa Stenius, Timo Bragge, Teija Parkkari, Anna-Maija Penttinen, Yi Chen, Omar S. Mabrouk, Kelly E. Glajch, Warren D. Hirst, Michael Perkinton, Terina N. Martinez, Mark A. Frasier

published 08 Aug 2025

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