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NK cells

Successful expansion and cryopreservation of human natural killer cell line NK-92 for clinical manufacturing

Seul Lee, Yunjoo Joo, Eun Ji Lee, Youngseon Byeon, Jae-Hwan Kim, Kyoung-Ho Pyo, Young Seob Kim, Sun Min Lim, Peter Kilbride, Rohin K. Iyer, Mingming Li, Mandy C. French, Jung-Yub Lee, Jeeheon Kang, Hyesin Byun, Byoung Chul Cho

published 23 Feb 2024

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Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody

Michela Centonze, Valentina Fiori, Maciej Kujawski, Lin Li, Patty Wong, Lindsay Williams, Tomas Di Mambro, Sabrina Dominici, Angelo Sparti, John E. Shively, Mauro Magnani

published 12 Feb 2024

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Pharmacokinetics, pharmacodynamics, and toxicity of a PD-1-targeted IL-15 in cynomolgus monkeys

Changhua Ji, Bing Kuang, Bernard S. Buetow, Allison Vitsky, Yuanming Xu, Tzu-Hsuan Huang, Javier Chaparro-Riggers, Eugenia Kraynov, Diane Matsumoto

published 05 Feb 2024

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Diverse modulatory effects of bibenzyls from Dendrobium species on human immune cell responses under inflammatory conditions

Virunh Kongkatitham, Adeline Dehlinger, Chatchai Chaotham, Kittisak Likhitwitayawuid, Chotima Böttcher, Boonchoo Sritularak

published 01 Feb 2024

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A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy

William J. Dower, Angie Inkyung Park, Alice V. Bakker, Steven E. Cwirla, Praechompoo Pongtornpipat, Blake M. Williams, Prarthana Joshi, Bryan A. Baxter, Michael C. Needels, Ronald W. Barrett

published 24 Oct 2023

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Establishment of anti-asialo-GM1 rabbit monoclonal antibodies capable of reducing natural killer cell activity in mice

Tatsuji Kimura, Satoshi Ohta, Hiroshi Murayama

published 09 Oct 2023

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Mouse methylation profiles for leukocyte cell types, and estimation of leukocyte fractions in inflamed gastrointestinal DNA samples

Kazuhiro Nishiyama, Hitomi Nishinakamura, Hideyuki Takeshima, Liu Yuyu, Chihiro Takeuchi, Naoko Hattori, Haruna Takeda, Satoshi Yamashita, Mika Wakabayashi, Kotomi Sato, Kazutaka Obama, Toshikazu Ushijima

published 05 Oct 2023

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Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab

Barry D. Hock, Liping Goddard, Sean A. MacPherson, Matthew Strother, David Gibbs, John F. Pearson, Judith L. McKenzie

published 15 Sep 2023

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Rapid increase in immune surveillance and expression of NKT and γδT cell activation markers after consuming a nutraceutical supplement containing Aloe vera gel, extracts of Poria cocos and rosemary. A randomized placebo-controlled cross-over trial

Liu Yu, Sage McGarry, Dina Cruickshank, Gitte S. Jensen

published 12 Sep 2023

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Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma

Beatrice M. Muriuki, Catherine S. Forconi, Erastus K. Kirwa, Titus K. Maina, Bonface O. Ariera, Jeffrey A. Bailey, Anita Ghansah, Ann M. Moormann, John M. Ong’echa

published 30 Aug 2023

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Identification of novel lactic acid bacteria with enhanced protective effects against influenza virus

Atsushi Sugimoto, Tomoe Numaguchi, Ryota Chihama, Yuto Takenaka, Yuuki Sato

published 09 Aug 2023

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Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles

Ana Moyano, Bongiwe Ndlovu, Msizi Mbele, Kewreshini Naidoo, Nasreen Khan, Jaclyn K. Mann, Thumbi Ndung’u

published 02 Jun 2023

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Delivery of a novel membrane-anchored Fc chimera enhances NK cell-mediated killing of tumor cells and persistently virus-infected cells

Namita Varudkar, Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja Copik, Griffith D. Parks

published 05 May 2023

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