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Neuronal differentiation

Hypothermia improves neuronal network recovery in a human-derived in vitro model of oxygen-deprivation

Eva J. H. F. Voogd, Marloes Thijs, Marloes R. Levers, Jeannette Hofmeijer, Monica Frega

published 20 Dec 2024

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n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs

Yu-Chen Deng, Jen-Wei Liu, Hsiao-Chien Ting, Tzu-Chen Kuo, Chia-Hung Chiang, En-Yi Lin, Horng-Jyh Harn, Shinn-Zong Lin, Chia-Yu Chang, Tzyy-Wen Chiou

published 07 Nov 2024

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Generation of isogenic models of Angelman syndrome and Prader-Willi syndrome in CRISPR/Cas9-engineered human embryonic stem cells

Rachel B. Gilmore, Dea Gorka, Christopher E. Stoddard, Pooja Sonawane, Justin Cotney, Stormy J. Chamberlain

published 01 Nov 2024

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Six3 and Six6 jointly control diverse target genes in multiple cell populations over developmental trajectories of mouse embryonic retinal progenitor cells

Alexander Ferrena, Xusheng Zhang, Rupendra Shrestha, Deyou Zheng, Wei Liu

published 24 Oct 2024

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Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo

Rodrigo Ibarra-García-Padilla, Annika Nambiar, Thomas A. Hamre, Eileen W. Singleton, Rosa A. Uribe

published 18 Sep 2024

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Carvedilol suppresses ryanodine receptor-dependent Ca²⁺ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer’s disease

Atsushi Hori, Haruka Inaba, Takashi Hato, Kimie Tanaka, Shoichi Sato, Mizuho Okamoto, Yuna Horiuchi, Faith Jessica Paran, Yoko Tabe, Shusuke Mori, Corina Rosales, Wado Akamatsu, Takashi Murayama, Nagomi Kurebayashi, Takashi Sakurai, Tomohiko Ai, Takashi Miida

published 22 Aug 2024

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Oligodendroglia-to-pericyte conversion after lipopolysaccharide exposure is gender-dependent

Qingting Yu, Linyuan Zhang, Ting Xu, Jiapeng Shao, Falei Yuan, Zuisu Yang, Yuncheng Wu, Haiyan Lyu

published 06 Aug 2024

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Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes

Maddie R. Lemieux, Bernhard Freigassner, Jessica L. Hanson, Zahra Thathey, Mark R. Opp, Charles A. Hoeffer, Christopher D. Link

published 25 Jun 2024

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Applying Spinal Cord Organoids as a quantitative approach to study the mammalian Hedgehog pathway

Markus Holzner, Anton Wutz, Giulio Di Minin

published 25 Jun 2024

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The bidirectional role of GABA_A and GABA_B receptors during the differentiation process of neural precursor cells of the subventricular zone

Nadia Estefanía Gutierrez-Castañeda, Vladimir Allex Martínez-Rojas, Lenin David Ochoa-de la Paz, Emilio J. Galván

published 24 Jun 2024

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FABP5-binding lipids regulate autophagy in differentiated SH-SY5Y cells

Alejandro Soto-Avellaneda, Alexandra E. Oxford, Fabio Halla, Peyton Vasquez, Emily Oe, Anton D. Pugel, Alyssa M. Schoenfeld, Matthew C. Tillman, André Cuevas, Eric A. Ortlund, Brad E. Morrison

published 20 Jun 2024

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PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs

Maryam Esmaeili, Mohammad Hossein Nasr-Esfahani, Alireza Shoaraye Nejati, Zahra Safaeinejad, Atefeh Atefi, Timothy L. Megraw, Kamran Ghaedi

published 16 May 2024

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Trolox and recombinant Irisin as a potential strategy to prevent neuronal damage induced by random positioning machine exposure in differentiated HT22 cells

Roberto Bonanni, Ida Cariati, Anna Maria Rinaldi, Mario Marini, Giovanna D’Arcangelo, Umberto Tarantino, Virginia Tancredi

published 21 Mar 2024

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