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Mutation detection

Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer

Florian Heitz, Sotirios Lakis, Philipp Harter, Sebastian Heikaus, Jalid Sehouli, Jatin Talwar, Roopika Menon, Beyhan Ataseven, Miriam Bertrand, Stephanie Schneider, Erika Mariotti, Mareike Bommert, Judith N. Müller, Sonia Prader, Frauke Leenders, Alexandra Hengsbach, Christian Gloeckner, Elena Ioana Braicu, Lukas C. Heukamp, Andreas du Bois, Johannes M. Heuckmann

published 07 Feb 2022

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Linking protein structural and functional change to mutation using amino acid networks

Cristina Sotomayor-Vivas, Enrique Hernández-Lemus, Rodrigo Dorantes-Gilardi

published 21 Jan 2022

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Limits to detecting epistasis in the fitness landscape of HIV

Avik Biswas, Allan Haldane, Ronald M. Levy

published 18 Jan 2022

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A short plus long-amplicon based sequencing approach improves genomic coverage and variant detection in the SARS-CoV-2 genome

Carlos Arana, Chaoying Liang, Matthew Brock, Bo Zhang, Jinchun Zhou, Li Chen, Brandi Cantarel, Jeffrey SoRelle, Lora V. Hooper, Prithvi Raj

published 13 Jan 2022

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Neonicotinoid’s resistance monitoring, diagnostic mechanisms and cytochrome P450 expression in green peach aphid [Myzus persicae (Sulzer) (Hemiptera: Aphididae)]

Muhammad Umair Sial, Khalid Mehmood, Shafqat Saeed, Mureed Husain, Khawaja Ghulam Rasool, Abdulrahman Saad Aldawood

published 12 Jan 2022

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Equivalence of the GeneXpert System and GeneXpert Omni System for tuberculosis and rifampicin resistance detection

Sophia B. Georghiou, Riccardo Alagna, Daniela M. Cirillo, Sergio Carmona, Morten Ruhwald, Samuel G. Schumacher

published 17 Dec 2021

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Performance of GenoType MTBDRsl assay for detection of second-line drugs and ethambutol resistance directly from sputum specimens of MDR-TB patients in Bangladesh

S. M. Mazidur Rahman, Rumana Nasrin, Arfatur Rahman, Shahriar Ahmed, Razia Khatun, Mohammad Khaja Mafij Uddin, Md. Mojibur Rahman, Sayera Banu

published 16 Dec 2021

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CD8+ cell somatic mutations in multiple sclerosis patients and controls—Enrichment of mutations in STAT3 and other genes implicated in hematological malignancies

Miko Valori, Lilja Jansson, Pentti J. Tienari

published 07 Dec 2021

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Mutational landscape of SARS-CoV-2 genome in Turkey and impact of mutations on spike protein structure

Ozden Hatirnaz Ng, Sezer Akyoney, Ilayda Sahin, Huseyin Okan Soykam, Gunseli Bayram Akcapinar, Ozkan Ozdemir, Derya Dilek Kancagi, Gozde Sir Karakus, Bulut Yurtsever, Ayse Sesin Kocagoz, Ercument Ovali, Ugur Ozbek

published 06 Dec 2021

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Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples

Nick P. G. Gauthier, Cassidy Nelson, Michael B. Bonsall, Kerstin Locher, Marthe Charles, Clayton MacDonald, Mel Krajden, Samuel D. Chorlton, Amee R. Manges

published 18 Nov 2021

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Rifampicin and isoniazid drug resistance among patients diagnosed with pulmonary tuberculosis in southwestern Uganda

Lisa Nkatha Micheni, Kennedy Kassaza, Hellen Kinyi, Ibrahim Ntulume, Joel Bazira

published 29 Oct 2021

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A novel xenonucleic acid-mediated molecular clamping technology for early colorectal cancer screening

Qing Sun, Larry Pastor, Jinwei Du, Michael J. Powell, Aiguo Zhang, Walter Bodmer, Jianzhong Wu, Shu Zheng, Michael Y. Sha

published 05 Oct 2021

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Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates

Barbara Schrörs, Pablo Riesgo-Ferreiro, Patrick Sorn, Ranganath Gudimella, Thomas Bukur, Thomas Rösler, Martin Löwer, Ugur Sahin

published 27 Sep 2021

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