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Mutation

Insertional Mutagenesis by CRISPR/Cas9 Ribonucleoprotein Gene Editing in Cells Targeted for Point Mutation Repair Directed by Short Single-Stranded DNA Oligonucleotides

Natalia Rivera-Torres, Kelly Banas, [ ... ], Eric B. Kmiec

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

Anne Cleasby, Jeff Yon, [ ... ], Thomas G. Davies

Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes

Randy Hecht, Yue-Sheng Li, [ ... ], Jing Xu

Pyocyanin Promotes Extracellular DNA Release in Pseudomonas aeruginosa

Theerthankar Das, Mike Manefield

DNA mutation motifs in the genes associated with inherited diseases

Michal Růžička, Petr Kulhánek, [ ... ], Kamila Réblová

Filtering for Compound Heterozygous Sequence Variants in Non-Consanguineous Pedigrees

Tom Kamphans, Peggy Sabri, [ ... ], Peter M. Krawitz

Development of New Mouse Lung Tumor Models Expressing EGFR T790M Mutants Associated with Clinical Resistance to Kinase Inhibitors

Lucia Regales, Marissa N. Balak, [ ... ], William Pao

Genomic Signatures of Strain Selection and Enhancement in Bacillus atrophaeus var. globigii, a Historical Biowarfare Simulant

Henry S. Gibbons, Stacey M. Broomall, [ ... ], Evan W. Skowronski

Genetic Mutations Associated with Isoniazid Resistance in Mycobacterium tuberculosis: A Systematic Review

Marva Seifert, Donald Catanzaro, Antonino Catanzaro, Timothy C. Rodwell

Applying Physics-Based Scoring to Calculate Free Energies of Binding for Single Amino Acid Mutations in Protein-Protein Complexes

Hege Beard, Anuradha Cholleti, [ ... ], Kathryn A. Loving

The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans

Yi Zhang, Zhiyong Shao, [ ... ], Jo Anne Powell-Coffman

Phenotype Sequencing: Identifying the Genes That Cause a Phenotype Directly from Pooled Sequencing of Independent Mutants

Marc A. Harper, Zugen Chen, [ ... ], Christopher J. Lee

Targeted Sequencing of Cancer-Related Genes in Colorectal Cancer Using Next-Generation Sequencing

Sae-Won Han, Hwang-Phill Kim, [ ... ], Tae-You Kim

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