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Mutation

The impact of mutations on TP53 protein and MicroRNA expression in HNSCC: Novel insights for diagnostic and therapeutic strategies

Ashraf Attia Mahmoud, Mohd Firdaus Raih, Edison Eukun Sage, Qurashi M. Ali, Omnia H. Suliman, Sabah A. E. Ibrahim, Osama Mohamed, Samar Abdelrazeg, Sofia B. Mohamed

published 07 May 2025

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CRISPR genome editing using a combined positive and negative selection system

Ishrya Sharma, Kerisa Hall, Shannon Moonah

published 06 May 2025

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High frequency of the PIK3CA H1047L mutation in Indonesian breast cancer across molecular subtypes

Yan Wisnu Prajoko, Didik Setyo Heriyanto, Bayu Tirta Dirja, Susanto Susanto, Vincent Lau, Andrew Nobiantoro Gunawan, Brigitta Natasya Halim, Nur Dina Amalina

published 05 May 2025

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Prognostic significance of KRAS, NRAS, BRAF, and PIK3CA mutations in stage II/III colorectal cancer: A retrospective study and meta-analysis

Di Kang, Jing Li, Yangyang Li, Jingquan Xu, Jianlei Yang, Zili Zhang

published 25 Apr 2025

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Identification of novel compound heterozygous variants in the PEX10 gene in a Han-Chinese family with PEX10-related peroxisome biogenesis disorders

Xiangjun Huang, Xinyue Deng, Xiong Deng, Hongbo Xu, Hao Deng, Lamei Yuan

published 23 Apr 2025

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Epidemiological and spatial analysis of newly diagnosed HIV-1/AIDS patients before antiretroviral therapy in Ningxia from 2020 to 2021

Yichang Liu, Xiaofa Ma, Jianxin Pei, Dongzhi Yang, Yufeng Li, Xiaohong Zhu, Zhonglan Wu

published 22 Apr 2025

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Gama rays mediated improvement of catalytic efficiency and thermostability of glucoamylase by replacing active site leucine to isoleucene from super koji (Aspergillus oryzae)

Anam Saqib, Saif -ur-Rehman, Hazrat Ali, Noor Hassan, Asad Ali, Muhammad Hamid Rashid

published 18 Apr 2025

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Predicting a failure of postoperative thromboprophylaxis in non-small cell lung cancer: A stacking machine learning approach

Ligang Hao, Junjie Zhang, Yonghui Di, Zheng Qi, Peng Zhang

published 01 Apr 2025

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Polymorphisms in Pfkelch13 domains before and after the introduction of artemisinin-based combination therapy in Southwest Nigeria

Abiodun Amusan, Olugbenga Akinola, Kazeem Akano, María Hernández-Castañeda, Jenna K. Dick, Akintunde Sowunmi, Geoffrey Hart, Grace Gbotosho

published 31 Mar 2025

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Genetic subtyping by Whole Exome Sequencing across Diffuse Large B Cell Lymphoma and Plasmablastic Lymphoma

Aitana Avendaño Pomares, Laura Rodríguez Merino, Sonia González, Jordi Morata, Raúl Tonda, Patricia Arribas, José Revert, Estrella Carrillo, Carlos Grande, Josep Maria Roncero, Jaime Pérez de Oteyza, Concepción Nicolás, Norma Gutierrez, Pau Abrisqueta, Antonio Gutiérrez, Ángel Ramírez-Páyer, Alejandro Martin Garcia-Sancho, Eva González-Barca, Santiago Montes-Moreno, on behalf of GELTAMO group (Grupo Español de Linfomas y Trasplante Autólogo de Medula Osea), Spain

published 11 Mar 2025

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Mis-splicing drives loss of function of p53^E224D point mutation

Ian C. Lock, Nathan H. Leisenring, Warren Floyd, Eric S. Xu, Lixia Luo, Yan Ma, Erin C. Mansell, Diana M. Cardona, Chang-Lung Lee, David G. Kirsch

published 05 Mar 2025

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Microevolution and phylogenomic study of Respiratory Syncytial Virus type A

Ashfaq Ahmad, Sidra Majaz, Aamir Saeed, Shumaila Noreen, Muhammad Abbas, Bilal Khan, Hamid Ur Rahman, Faisal Nouroz, Yingqiu Xie, Abdur Rashid, Atta Ur Rehman

published 25 Feb 2025

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SARS-CoV-2 Omicron subvariant genomic variation associations with immune evasion in Northern California: A retrospective cohort study

Joshua R. Nugent, Mariah S. Wood, Liyan Liu, Teal Bullick, Jeffrey M. Schapiro, Phacharee Arunleung, Gautham Gautham, Shiffen Getabecha, Christina Morales, Laura B. Amsden, Crystal A. Hsiao, Debra A. Wadford, Stacia K. Wyman, Jacek Skarbinski

published 24 Feb 2025

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