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Mutation

18 individual genes underwent variant screening in a northwest Chinese group comprised 83 probands diagnosed with early-onset high myopia

Yang Liu, Shao-Chi Zhang, Wen Zhang, Zhong-Qi Xue, Yi-Xuan Qin, Shun-Yu Piao, Wen-Jing Li, Meng-Li Ji, Wen-Juan Zhuang

published 08 Sep 2025

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The role of cyclic di-GMP in biomaterial-associated infections caused by commensal Escherichia coli

Shanshan Li, Chengwei Bi, Bingquan Xiang, Zhonghui Wang, Hui Yang, Chaojiang Fu, Lianpu Chen, Ying Chen

published 20 Aug 2025

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Ribitol treatment rescues dystroglycanopathy mice with common L276I mutation

Bo Wu, Pei Juan Lu, Morgan Drains, Sapana Shah, Anthony Blaeser, Victoria Leroy, Jessalyn Killilee, Molly Holbrook, Qi Long Lu

published 20 Aug 2025

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Superoxide dismutase VPA1514 in Vibrio parahaemolyticus protects against environmental stresses

Paula Hsu, Hin-chung Wong, Chung-Tao Tang

published 14 Aug 2025

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Passage of human-origin influenza A virus in swine tracheal epithelial cells selects for adaptive mutations in the hemagglutinin gene

Jongsuk Mo, Lucas M. Ferreri, Ginger Geiger, Daniel R. Perez, Daniela S. Rajao

published 13 Aug 2025

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CRISPR-Cas9 targeting the bla_KPC gene in a clinical isolate of Klebsiella michiganensis: Reduction of imipenem resistance and changes in genomic carbapenem resistance determinants

Thaysa Leite Tagliaferri, Alex Krüttgen, Tiago Antônio de Oliveira Mendes, Simone Gonçalves dos Santos, Hans-Peter Horz

published 12 Aug 2025

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Evaluation of therapeutic agent selection based on comprehensive genomic profiling in gastroenteropancreatic neuroendocrine neoplasms

Suguru Miyazawa, Hiroaki Ono, Hironari Yamashita, Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Satoru Aoyama, Naoya Ishibashi, Keiichi Akahoshi, Sadakatsu Ikeda, Minoru Tanabe

published 06 Aug 2025

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Prevalence of HIV drug resistance, its correlates and common mutations among people living with HIV failing on ART in northern Uganda: A cross-sectional study

Francis Kayinda, Phyllis Awor, Twaha Mahaba, Alex M. Muganzi, Joanita Kigozi, Patrick Odong Olwedo, Esther M. Nasuuna, Robert Mutumba, Rhoda Wanyenze

published 05 Aug 2025

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CRISPR/Cas9-targeted smpB mutation revealing roles in biofilm formation, motility, and antibiotic susceptibility in Acinetobacter baumannii

Techit Thavorasak, Sirijan Santajit, Witawat Tunyong, Thida Kong-Ngoen, Onrapak Reamtong, Sumate Ampawong, Nawannaporn Saelim, Thapani Srisai, Pisinee Aiumurai, Pornpan Pumirat, Wanpen Chaicumpa, Nitaya Indrawattana

published 04 Aug 2025

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Identification of the Francisella novicida FTN_0096 as a factor involved in intracellular replication and host response

Dhandy Koesoemo Wardhana, Takashi Shimizu, Kenta Watanabe, Akihiko Uda, Masahisa Watarai

published 01 Aug 2025

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Prevalence and diagnostic reliability of BRAF, RAS mutations, and RET/PTC rearrangements in a Latin American public health service population with thyroid nodular disease

Freddy David Moposita Molina, Grasiela Agnes, Marília Remuzzi Zandoná, Rogério Izquierdo, Fábio Alves Bilhar, Laura Berton Eidt, Virgílio Gonzales Zanella, Luiz Felipe Osowski, Sofia de Oliveira Belardinelli, Amanda Cometti de Andrade, Erika Laurini de Souza Meyer, Lenara Golbert, Vanessa Suñé Mattevi

published 01 Aug 2025

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Derivation of a novel multi‐gene prognostic model based on regulated cell death pathways in acute myeloid leukemia: A comprehensive bioinformatic analysis integrating gene expression, mutation profiling, and immune infiltration

Ali Ahmadi, Amir Abas Navidinia, Davood Bashash, Behzad Poopak, Shadi Esmaeili

published 01 Aug 2025

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Apparent differences between human and chimp proteomes are reduced when considering human population: Human specific variants are enriched in disordered and compositionally biased regions

Pablo Mier, Miguel A. Andrade-Navarro, Enrique Morett

published 31 Jul 2025

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