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Mutation

Off-target sequence variations driven by the intrinsic properties of the Cas–sgRNA–DNA complex in genome editing

Celine Kurniawan, Takeshi Itoh

published 18 Jul 2025

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Identification of genetic variations linked to buparvaquone resistance in Theileria annulata infecting dairy cattle in India

Pankaj Musale, Ajinkya Khilari, Rohini Gade, Velu Dhanikachalam, Santoshkumar Jadhav, Manali Bajpai, Bhagya Turakani, Akshay Joshi, Amar Prajapati, Anand Srivastava, Marimuthu Swaminathan, Sachin Joshi, Dhanasekaran Shanmugam

published 18 Jul 2025

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Optimization of the prostaglandin F_2α receptor for structural biology

Marine Salze, Sébastien Chrétien, Tegvir S. Boora, Madalina Macovei, Eric Barbeau, Véronique Blais, Stéphane A. Laporte, Martin Audet

published 18 Jul 2025

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Decoding Myosin-3 mutational hotspots: Linking deleterious variants to Duchenne muscular dystrophy severity and psychiatric comorbidities

Mohammed Ageeli Hakami, Ahad Amer Alsaiari, Taj Mohammad, Anas Shamsi

published 15 Jul 2025

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Linking genetic and phenotypic bedaquiline resistance in Mycobacterium tuberculosis strains from Georgia

Nino Maghradze, Chloé Loiseau, Galo Adrian Goig, Nino Bablishvili, Levan Jugheli, Sonia Borrell, Nestani Tukvadze, Russell Ryan Kempker, Zaza Avaliani, Sebastien Gagneux

published 15 Jul 2025

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Men in menopause? Experimental verification of the mate choice theory with Drosophila melanogaster shows both sexes can undergo menopause

Divya Purohith, Mitali Chaudhary, Alyssa Gomes, Nina Rajapakse, Aditi Das, Neha Dhanvanthry, Michelle Brown, Manan Mukherjee, Rama S. Singh

published 03 Jul 2025

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Next-Generation Sequencing (NGS) in non-small cell lung carcinoma: A real-world experience in the public health system of Galicia (Northwest Spain)

Ihab Abdulkader-Nallib, José Manuel Cameselle-Teijeiro, Iván Lesende-Rodríguez, Raquel Pérez-Becerra, José Ramón Antúnez-López, Jorge García-González, Luis León-Mateos, María Sánchez-Ares

published 01 Jul 2025

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Using computer-generated protein models to analyze mutations linked to Amelogenesis Imperfecta

Nazlee Sharmin, Jerald Yuan, Ava K. Chow

published 26 Jun 2025

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Whole genome sequencing revealed esophageal squamous cell carcinoma related biomarkers

Mingjun Li, Lei Li, Xizi Wang, Yanwei Zhao, Peina Du, Wei Wang, Zhenxing Wang, Yadong Wang, Yanxing Sheng, Mingliang Gu, Xiaodong Jia

published 26 Jun 2025

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Evaluation of potential of targeted sequencing through mutational signature simulation

Keisuke Kodama, Yiwei Ling, Hiroshi Ichikawa, Toshifumi Wakai, Shujiro Okuda

published 25 Jun 2025

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Prevalence and spectrum of germline BRCA1 and BRCA2 mutations in multiethnic cohort of breast cancer patients in Brunei Darussalam

Siti Nur Idayu Matusin, Nuramalina Mumin, Hazirah Zainal Abidin, Fatin Nurizzati Mohd Jaya, Zen Huat Lu, Mas Rina Wati Haji Abdul Hamid

published 18 Jun 2025

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Characterization of the genomic landscape of canine oral osteosarcoma reveals similarities with appendicular osteosarcoma

Christopher Husted, Sarah Adrianowycz, Cornelia Peterson, Suzanne Bartholf DeWitt, Elinor K. Karlsson, William Eward, Jason A. Somarelli, Kate Megquier, Heather L. Gardner

published 10 Jun 2025

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SARS-COV-2 mutations in North Rift, Kenya

Elius Mbogori, Kelvin Thiongo, Harrison Yunying Deng, Caroline Wangui Gikunyu, Winfrida Cheriro, Stanslaus Musyoki, Richard Biegon, Damaris Matoke-Muhia, Kirtika Patel, Binhua Liang, Elijah Songok

published 06 Jun 2025

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