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Mutation

Constitutive Activation of the Thyroid-Stimulating Hormone Receptor (TSHR) by Mutating Ile⁶⁹¹ in the Cytoplasmic Tail Segment

Zheng Liu, Feiyue Fan, Xiangjun Xiao, Yuanming Sun

Point Mutations in Aβ Result in the Formation of Distinct Polymorphic Aggregates in the Presence of Lipid Bilayers

Phillip M. Pifer, Elizabeth A. Yates, Justin Legleiter

Laboratory-Evolved Mutants of an Exogenous Global Regulator, IrrE from Deinococcus radiodurans, Enhance Stress Tolerances of Escherichia coli

Tingjian Chen, Jianqing Wang, [ ... ], Zhanglin Lin

DIA1R Is an X-Linked Gene Related to Deleted In Autism-1

Azhari Aziz, Sean P. Harrop, Naomi E. Bishop

K70Q Adds High-Level Tenofovir Resistance to “Q151M Complex” HIV Reverse Transcriptase through the Enhanced Discrimination Mechanism

Atsuko Hachiya, Eiichi N. Kodama, [ ... ], Stefan G. Sarafianos

The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation

Chai Ann Ng, Mark J. Hunter, [ ... ], Jamie I. Vandenberg

Structure-Based Analysis of Five Novel Disease-Causing Mutations in 21-Hydroxylase-Deficient Patients

Carolina Minutolo, Alejandro D. Nadra, [ ... ], Liliana Dain

Identification of a Key Amino Acid of LuxS Involved in AI-2 Production in Campylobacter jejuni

Paul Plummer, Jinge Zhu, [ ... ], Qijing Zhang

Allosteric Interactions between the Myristate- and ATP-Site of the Abl Kinase

Roxana E. Iacob, Jianming Zhang, Nathanael S. Gray, John R. Engen

Lysine Auxotrophy Combined with Deletion of the SecA2 Gene Results in a Safe and Highly Immunogenic Candidate Live Attenuated Vaccine for Tuberculosis

Joseph Hinchey, Bo Y. Jeon, [ ... ], Sunhee Lee

Detection of Resistance Mutations to Antivirals Oseltamivir and Zanamivir in Avian Influenza A Viruses Isolated from Wild Birds

Goran Orozovic, Kanita Orozovic, Johan Lennerstrand, Björn Olsen

Nonsense Mediated Decay Resistant Mutations Are a Source of Expressed Mutant Proteins in Colon Cancer Cell Lines with Microsatellite Instability

David S. Williams, Matthew J. Bird, [ ... ], Antony W. Burgess

Mutation Detection with Next-Generation Resequencing through a Mediator Genome

Omri Wurtzel, Mally Dori-Bachash, [ ... ], Rotem Sorek

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