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Mutation

Using Genomic Sequencing for Classical Genetics in E. coli K12

Eric Lyons, Michael Freeling, Sydney Kustu, William Inwood

Genetic Analysis of the Functions and Interactions of Components of the LevQRST Signal Transduction Complex of Streptococcus mutans

Lin Zeng, Satarupa Das, Robert A. Burne

Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

Scott E. Hensley, Suman R. Das, [ ... ], Jonathan W. Yewdell

Subjects with Molecularly Defined Familial Hypercholesterolemia or Familial Defective apoB-100 Are Not Being Adequately Treated

Trond P. Leren, Knut Erik Berge

Phenotype Sequencing: Identifying the Genes That Cause a Phenotype Directly from Pooled Sequencing of Independent Mutants

Marc A. Harper, Zugen Chen, [ ... ], Christopher J. Lee

Functional Characterization of Human Cancer-Derived TRKB Mutations

Thomas R. Geiger, Ji-Ying Song, Aranzazu Rosado, Daniel S. Peeper

Interplay between Kinase Domain Autophosphorylation and F-Actin Binding Domain in Regulating Imatinib Sensitivity and Nuclear Import of BCR-ABL

Martin Preyer, Paolo Vigneri, Jean Y. J. Wang

Loss of Nuclear Activity of the FBXO7 Protein in Patients with Parkinsonian-Pyramidal Syndrome (PARK15)

Tianna Zhao, Esther De Graaff, [ ... ], Vincenzo Bonifati

Modeling Retinal Degeneration Using Patient-Specific Induced Pluripotent Stem Cells

Zi-Bing Jin, Satoshi Okamoto, [ ... ], Masayo Takahashi

Efficient Nuclear Transport of Structurally Disturbed Cargo: Mutations in a Cargo Protein Switch Its Cognate Karyopherin

Susana R. Chaves, Jonathan S. Rosenblum

Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing

Sandra Cristea, Philip D. Gregory, Fyodor D. Urnov, Gregory J. Cost

2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP⁺-Dependent Isocitrate Dehydrogenase Mutations

Genglin Jin, Zachary J. Reitman, [ ... ], Hai Yan

Two-Component System RgfA/C Activates the fbsB Gene Encoding Major Fibrinogen-Binding Protein in Highly Virulent CC17 Clone Group B Streptococcus

Rim Al Safadi, Laurent Mereghetti, [ ... ], Agnès Rosenau

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