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Mutation

Physiological Levels of Pik3ca^H1047R Mutation in the Mouse Mammary Gland Results in Ductal Hyperplasia and Formation of ERα-Positive Tumors

Anjali Tikoo, Vincent Roh, Karen G. Montgomery, Ivan Ivetac, Paul Waring, Rebecca Pelzer, Lauren Hare, Mark Shackleton, Patrick Humbert, Wayne A. Phillips

published 30 May 2012

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Mdm2 RING Mutation Enhances p53 Transcriptional Activity and p53-p300 Interaction

Hilary V. Clegg, Yoko Itahana, Koji Itahana, Sundhar Ramalingam, Yanping Zhang

published 29 May 2012

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p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors

Joern Henze, Thomas Mühlenberg, Susanne Simon, Florian Grabellus, Brian Rubin, Georg Taeger, Martin Schuler, Juergen Treckmann, Maria Debiec-Rychter, Takahiro Taguchi, Jonathan A. Fletcher, Sebastian Bauer

published 25 May 2012

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Low Dose Vaccination with Attenuated Francisella tularensis Strain SchuS4 Mutants Protects against Tularemia Independent of the Route of Vaccination

Dedeke Rockx-Brouwer, Audrey Chong, Tara D. Wehrly, Robert Child, Deborah D. Crane, Jean Celli, Catharine M. Bosio

published 25 May 2012

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Genotype-Dependent Efficacy of a Dual PI3K/mTOR Inhibitor, NVP-BEZ235, and an mTOR Inhibitor, RAD001, in Endometrial Carcinomas

Keiko Shoji, Katsutoshi Oda, Tomoko Kashiyama, Yuji Ikeda, Shunsuke Nakagawa, Kenbun Sone, Yuichiro Miyamoto, Haruko Hiraike, Michihiro Tanikawa, Aki Miyasaka, Takahiro Koso, Yoko Matsumoto, Osamu Wada-Hiraike, Kei Kawana, Hiroyuki Kuramoto, Frank McCormick, Hiroyuki Aburatani, Tetsu Yano, Shiro Kozuma, Yuji Taketani

published 25 May 2012

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Relative Effectiveness of Mating Success and Sperm Competition at Eliminating Deleterious Mutations in Drosophila melanogaster

Sean C. A. Clark, Nathaniel P. Sharp, Locke Rowe, Aneil F. Agrawal

published 25 May 2012

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The ter Mutation in the Rat Dnd1 Gene Initiates Gonadal Teratomas and Infertility in Both Genders

Emily Northrup, Nils-Holger Zschemisch, Regina Eisenblätter, Silke Glage, Dirk Wedekind, Edwin Cuppen, Martina Dorsch, Hans-Jürgen Hedrich

published 24 May 2012

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Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

Finola E. Moore, Deepak Reyon, Jeffry D. Sander, Sarah A. Martinez, Jessica S. Blackburn, Cyd Khayter, Cherie L. Ramirez, J. Keith Joung, David M. Langenau

published 24 May 2012

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Full-Exon Pyrosequencing Screening of BRCA Germline Mutations in Mexican Women with Inherited Breast and Ovarian Cancer

Felipe Vaca-Paniagua, Rosa María Alvarez-Gomez, Verónica Fragoso-Ontiveros, Silvia Vidal-Millan, Luis Alonso Herrera, David Cantú, Enrique Bargallo-Rocha, Alejandro Mohar, César López-Camarillo, Carlos Pérez-Plasencia

published 24 May 2012

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Impact of Isoniazid Resistance-Conferring Mutations on the Clinical Presentation of Isoniazid Monoresistant Tuberculosis

Raymund Dantes, John Metcalfe, Elizabeth Kim, Midori Kato-Maeda, Philip C. Hopewell, Masae Kawamura, Payam Nahid, Adithya Cattamanchi

published 23 May 2012

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Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection

Taísa Magnani Dinamarco, Fernanda Zanolli Freitas, Ricardo S. Almeida, Neil Andrew Brown, Thaila Fernanda dos Reis, Leandra Naira Zambelli Ramalho, Marcela Savoldi, Maria Helena S. Goldman, Maria Célia Bertolini, Gustavo Henrique Goldman

published 23 May 2012

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Mutations in an AP2 Transcription Factor-Like Gene Affect Internode Length and Leaf Shape in Maize

Fukun Jiang, Mei Guo, Fang Yang, Keith Duncan, David Jackson, Antoni Rafalski, Shoucai Wang, Bailin Li

published 23 May 2012

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Paired Tumor and Normal Whole Genome Sequencing of Metastatic Olfactory Neuroblastoma

Glen J. Weiss, Winnie S. Liang, Tyler Izatt, Shilpi Arora, Irene Cherni, Robert N. Raju, Galen Hostetter, Ahmet Kurdoglu, Alexis Christoforides, Shripad Sinari, Angela S. Baker, Raghu Metpally, Waibhav D. Tembe, Lori Phillips, Daniel D. Von Hoff, David W. Craig, John D. Carpten

published 23 May 2012

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