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Mutation

Generation of TALEN-Mediated GR^dim Knock-In Rats by Homologous Recombination

Verónica Ponce de León, Anne-Marie Mérillat, Laurent Tesson, Ignacio Anegón, Edith Hummler

published 11 Feb 2014

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Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene

Yukinori Okada, Dorothee Diogo, Jeffrey D. Greenberg, Faten Mouassess, Walid A. L. Achkar, Robert S. Fulton, Joshua C. Denny, Namrata Gupta, Daniel Mirel, Stacy Gabriel, Gang Li, Joel M. Kremer, Dimitrios A. Pappas, Robert J. Carroll, Anne E. Eyler, Gosia Trynka, Eli A. Stahl, Jing Cui, Richa Saxena, Marieke J. H. Coenen, Henk-Jan Guchelaar, Tom W. J. Huizinga, Philippe Dieudé, Xavier Mariette, Anne Barton, Helena Canhão, João E. Fonseca, Niek de Vries, Paul P. Tak, Larry W. Moreland, S. Louis Bridges Jr, Corinne Miceli-Richard, Hyon K. Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, Towfique Raj, Philip L. De Jager, Soumya Raychaudhuri, Jane Worthington, Leonid Padyukov, Lars Klareskog, Katherine A. Siminovitch, Peter K. Gregersen, Elaine R. Mardis, Thurayya Arayssi, Layla A. Kazkaz, Robert M. Plenge

published 10 Feb 2014

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Combined Genetic and High-Throughput Strategies for Molecular Diagnosis of Inherited Retinal Dystrophies

Marta de Castro-Miró, Esther Pomares, Laura Lorés-Motta, Raul Tonda, Joaquín Dopazo, Gemma Marfany, Roser Gonzàlez-Duarte

published 07 Feb 2014

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Increase in Ethanol Yield via Elimination of Lactate Production in an Ethanol-Tolerant Mutant of Clostridium thermocellum

Ranjita Biswas, Sandeep Prabhu, Lee R. Lynd, Adam M. Guss

published 07 Feb 2014

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Identification and Glycerol-Induced Correction of Misfolding Mutations in the X-Linked Mental Retardation Gene CASK

Leslie E. W. LaConte, Vrushali Chavan, Konark Mukherjee

published 05 Feb 2014

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Chimeras of p14ARF and p16: Functional Hybrids with the Ability to Arrest Growth

Richard T. Williams, Lisa M. Barnhill, Huan-Hsien Kuo, Wen-Der Lin, Ayse Batova, Alice L. Yu, Mitchell B. Diccianni

published 05 Feb 2014

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Distinct Domains within the Human Cytomegalovirus U_L26 Protein Are Important for Wildtype Viral Replication and Virion Stability

Chun Mathers, Cody M. Spencer, Joshua Munger

published 05 Feb 2014

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The Arrival of the Frequent: How Bias in Genotype-Phenotype Maps Can Steer Populations to Local Optima

Steffen Schaper, Ard A. Louis

published 05 Feb 2014

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Escherichia coli Deletion Mutants Illuminate Trade-Offs between Growth Rate and Flux through a Foreign Anabolic Pathway

Kelly C. Falls, Aimee L. Williams, Anton V. Bryksin, Ichiro Matsumura

published 04 Feb 2014

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A Novel Angiotensin I-Converting Enzyme Mutation (S333W) Impairs N-Domain Enzymatic Cleavage of the Anti-Fibrotic Peptide, AcSDKP

Sergei M. Danilov, Michael S. Wade, Sylva L. Schwager, Ross G. Douglas, Andrew B. Nesterovitch, Isolda A. Popova, Kyle D. Hogarth, Nakul Bhardwaj, David E. Schwartz, Edward D. Sturrock, Joe G. N. Garcia

published 04 Feb 2014

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Next Generation Sequencing Improves the Accuracy of KRAS Mutation Analysis in Endoscopic Ultrasound Fine Needle Aspiration Pancreatic Lesions

Dario de Biase, Michela Visani, Paola Baccarini, Anna Maria Polifemo, Antonella Maimone, Adele Fornelli, Adriana Giuliani, Nicola Zanini, Carlo Fabbri, Annalisa Pession, Giovanni Tallini

published 04 Feb 2014

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Polydiacetylene-Based High-Throughput Screen for Surfactin Producing Strains of Bacillus subtilis

Lingyan Zhu, Qing Xu, Ling Jiang, He Huang, Shuang Li

published 03 Feb 2014

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The Ability to Form Homodimers Is Essential for RDM1 to Function in RNA-Directed DNA Methylation

Taku Sasaki, Zdravko J. Lorković, Shih-Chieh Liang, Antonius J. M. Matzke, Marjori Matzke

published 03 Feb 2014

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