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Mutation

Quantification and Dynamic Monitoring of EGFR T790M in Plasma Cell-Free DNA by Digital PCR for Prognosis of EGFR-TKI Treatment in Advanced NSCLC

Zhijie Wang, Rui Chen, [ ... ], Jie Wang

RNA Cytidine Acetyltransferase of Small-Subunit Ribosomal RNA: Identification of Acetylation Sites and the Responsible Acetyltransferase in Fission Yeast, Schizosaccharomyces pombe

Masato Taoka, Daisuke Ishikawa, [ ... ], Toshiaki Isobe

A Novel Simple Assay System to Quantify the Percent HCV-RNA Levels of NS5A Y93H Mutant Strains and Y93 Wild-Type Strains Relative to the Total HCV-RNA Levels to Determine the Indication for Antiviral Therapy with NS5A Inhibitors

Yoshihito Uchida, Jun-ichi Kouyama, Kayoko Naiki, Satoshi Mochida

Characterization of a Spontaneous Novel Mutation in the NPC2 Gene in a Cat Affected by Niemann Pick Type C Disease

Stefania Zampieri, Ezio Bianchi, [ ... ], Andrea Dardis

Protein Thermal Stability Enhancement by Designing Salt Bridges: A Combined Computational and Experimental Study

Chi-Wen Lee, Hsiu-Jung Wang, Jenn-Kang Hwang, Ching-Ping Tseng

Homozygosity Mapping and Whole Exome Sequencing Reveal a Novel Homozygous COL18A1 Mutation Causing Knobloch Syndrome

Alireza Haghighi, Amit Tiwari, [ ... ], Wolfgang Berger

Resequencing and Association Analysis of PTPRA, a Possible Susceptibility Gene for Schizophrenia and Autism Spectrum Disorders

Jingrui Xing, Chenyao Wang, [ ... ], Norio Ozaki

Molecular Dynamics Studies of the Inhibitor C34 Binding to the Wild-Type and Mutant HIV-1 gp41: Inhibitory and Drug Resistant Mechanism

Xueting Ma, Jianjun Tan, [ ... ], Cunxin Wang

Clonal Architectures and Driver Mutations in Metastatic Melanomas

Li Ding, Minjung Kim, [ ... ], Jeffrey S. Weber

Analysis of Non-Typeable Haemophilous influenzae VapC1 Mutations Reveals Structural Features Required for Toxicity and Flexibility in the Active Site

Brooke Hamilton, Alexander Manzella, [ ... ], J. Scott Butler

Revisiting Robustness and Evolvability: Evolution in Weighted Genotype Spaces

Raghavendran Partha, Karthik Raman

Somatic Mutations Favorable to Patient Survival Are Predominant in Ovarian Carcinomas

Wensheng Zhang, Andrea Edwards, Erik Flemington, Kun Zhang

Whole-Genome Sequencing of the World’s Oldest People

Hinco J. Gierman, Kristen Fortney, [ ... ], Stuart K. Kim

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