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Mutation

Mutations in the Catalytic Loop HRD Motif Alter the Activity and Function of Drosophila Src64

Taylor C. Strong, Gurvinder Kaur, Jeffrey H. Thomas

Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development

Gerard J. P. van Westen, Jörg K. Wegner, [ ... ], Andreas Bender

β Subunit M2–M3 Loop Conformational Changes Are Uncoupled from α1 β Glycine Receptor Channel Gating: Implications for Human Hereditary Hyperekplexia

Qiang Shan, Lu Han, Joseph W. Lynch

A Novel Mutation in the HSD17B10 Gene of a 10-Year-Old Boy with Refractory Epilepsy, Choreoathetosis and Learning Disability

Laurie H. Seaver, Xue-Ying He, [ ... ], Song-Yu Yang

A Novel Splicing Mutation Alters DSPP Transcription and Leads to Dentinogenesis Imperfecta Type II

Jun Zhang, Jiucun Wang, [ ... ], Jie Liu

Evolution and Adaptation in Pseudomonas aeruginosa Biofilms Driven by Mismatch Repair System-Deficient Mutators

Adela M. Luján, María D. Maciá, [ ... ], Andrea M. Smania

The N-Terminal Domain and Glycosomal Localization of Leishmania Initial Acyltransferase LmDAT Are Important for Lipophosphoglycan Synthesis

Gada K. Al-Ani, Nipul Patel, [ ... ], Rachel Zufferey

Modern and Ancestral Genotypes of Mycobacterium tuberculosis from Andhra Pradesh, India

Shirly K. Thomas, Chitra C. Iravatham, [ ... ], Niyaz Ahmed

Antimutator Alleles of Yeast DNA Polymerase Gamma Modulate the Balance between DNA Synthesis and Excision

Françoise Foury, Karolina Szczepanowska

Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors

Jan Jakubík, Helena Janíčková, [ ... ], Vladimír Doležal

Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration

Xinhua Shu, Ulrich F. O. Luhmann, [ ... ], Alan F. Wright

Can Linear Regression Modeling Help Clinicians in the Interpretation of Genotypic Resistance Data? An Application to Derive a Lopinavir-Score

Alessandro Cozzi-Lepri, Mattia C. F. Prosperi, [ ... ], for the EuroSIDA and the United Kingdom CHIC/United Kingdom HDRD Studies

Mitochondrial DNA Haplogroup Background Affects LHON, but Not Suspected LHON, in Chinese Patients

A-Mei Zhang, Xiaoyun Jia, [ ... ], Yong-Gang Yao

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