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Mouse models

Optimized processing of Gardenia Fruits with ginger juice: Unveiling therapeutic mechanisms for cholestatic liver injury through TLR4/NF-κB, FXR/PPAR-α, and PI3K/AKT/GSK-3β

Chenzi Lyu, Xianglong Meng, [ ... ], Hyo Won Jung

KYLO-0603, a novel liver-targeting, thyroid hormone receptor-β agonist for the inhibition of MASH progression

Xueqin lu, Shengjun Wang, [ ... ], Kunyuan Cui

ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD mice

Sohee Jeon, Alia O. Alia, [ ... ], Leah K. Cuddy

Validation of the FVB/N-Tg(HSA* LR)20bCath mice of myotonic dystrophy using swallowing function assessment, histology, and immunofluorescence analysis

Rie Asayama, Kaori Tanaka-Nishikubo, [ ... ], Naohito Hato

Role of c-Myc activating the transcription of PD-L1 in immune escape during benzene-induced malignant transformation of human lymphoblasts

Qihao Huang, Biyan Ye, [ ... ], Huanwen Tang

The molecular components of the anti-inflammatory cholinergic pathway are extrasplenic

Warda Merchant, Steven Wyler, Bandy Chen, Laurent Gautron

Role of mTORC1 signaling in postnatal microglia activation preceding neurodegeneration in a mouse model for Niemann-Pick disease Type C

Caroline E. Murray, David S. Betancourt-Trompa, [ ... ], Ileana Soto

Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome

Shunsuke Baba, Satoko Shinjo, [ ... ], Susumu Minamisawa

Identification of immune-related biomarkers associated with allergic rhinitis and development of a sample diagnostic model

MaoMeng Wang, Shuang Wang, [ ... ], Hua Zhang

A cytotoxic peptide-drug conjugate for tumor-specific delivery of co-injected molecules

Norio Miyamura, Chisato M. Yamazaki, [ ... ], Kazuki N. Sugahara

Anti-aging effect of low molecular weight recombinant humanized collagen on photo-aging by activating adherence junction signaling pathways

Kan Tao, Huilin Zhu, Jing Wei

TGFBR1 gene silencing attenuates cardiomyopathy in the HFpEF mouse model

Xuanyang Shen, Weidong Li, [ ... ], Guoping Kang

β-aminopropionitrile-induced thoracic aortopathy is refractory to cilostazol and sildenafil in mice

Samuel C. Tyagi, Sohei Ito, [ ... ], Hisashi Sawada

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