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Mouse models

Development of Functional Human NK Cells in an Immunodeficient Mouse Model with the Ability to Provide Protection against Tumor Challenge

Amanda Kwant-Mitchell, Elishka A. Pek, Kenneth L. Rosenthal, Ali A. Ashkar

published 21 Dec 2009

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Allergen Challenge Induces Ifng Dependent GTPases in the Lungs as Part of a Th1 Transcriptome Response in a Murine Model of Allergic Asthma

Nilesh Dharajiya, Swapnil Vaidya, Mala Sinha, Bruce Luxon, Istvan Boldogh, Sanjiv Sur

published 21 Dec 2009

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P21^cip-Overexpression in the Mouse β Cells Leads to the Improved Recovery from Streptozotocin-Induced Diabetes

Jie Yang, Weiqi Zhang, Wei Jiang, Xiaoning Sun, Yuhua Han, Mingxiao Ding, Yan Shi, Hongkui Deng

published 17 Dec 2009

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Cardiac Glycosides Induce Cell Death in Human Cells by Inhibiting General Protein Synthesis

Andrea Perne, Markus K. Muellner, Magdalena Steinrueck, Nils Craig-Mueller, Julia Mayerhofer, Ilse Schwarzinger, Mathew Sloane, Iris Z. Uras, Gregor Hoermann, Sebastian M. B. Nijman, Matthias Mayerhofer

published 16 Dec 2009

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Dopamine D2 Receptor Stimulation Potentiates PolyQ-Huntingtin-Induced Mouse Striatal Neuron Dysfunctions via Rho/ROCK-II Activation

Carole Deyts, Beatriz Galan-Rodriguez, Elodie Martin, Nicolas Bouveyron, Emmanuel Roze, Delphine Charvin, Jocelyne Caboche, Sandrine Bétuing

published 15 Dec 2009

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Immunological Memory Transferred with CD4 T Cells Specific for Tuberculosis Antigens Ag85B-TB10.4: Persisting Antigen Enhances Protection

Darragh Duffy, Amina Dawoodji, Else Marie Agger, Peter Andersen, Jürgen Westermann, Eric B. Bell

published 14 Dec 2009

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P-Glycoprotein Acts as an Immunomodulator during Neuroinflammation

Gijs Kooij, Ronald Backer, Jasper J. Koning, Arie Reijerkerk, Jack van Horssen, Susanne M. A. van der Pol, Joost Drexhage, Alfred Schinkel, Christine D. Dijkstra, Joke M. M. den Haan, Teunis B. H. Geijtenbeek, Helga E. de Vries

published 08 Dec 2009

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Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis

Simone Wüst, Denise Tischner, Michael John, Jan P. Tuckermann, Christiane Menzfeld, Uwe-Karsten Hanisch, Jens van den Brandt, Fred Lühder, Holger M. Reichardt

published 07 Dec 2009

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Characterization of Detergent-Insoluble Proteins in ALS Indicates a Causal Link between Nitrative Stress and Aggregation in Pathogenesis

Manuela Basso, Giuseppina Samengo, Giovanni Nardo, Tania Massignan, Giuseppina D'Alessandro, Silvia Tartari, Lavinia Cantoni, Marianna Marino, Cristina Cheroni, Silvia De Biasi, Maria Teresa Giordana, Michael J. Strong, Alvaro G. Estevez, Mario Salmona, Caterina Bendotti, Valentina Bonetto

published 02 Dec 2009

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Loss of PDZK1 Causes Coronary Artery Occlusion and Myocardial Infarction in Paigen Diet-Fed Apolipoprotein E Deficient Mice

Ayce Yesilaltay, Kathleen Daniels, Rinku Pal, Monty Krieger, Olivier Kocher

published 01 Dec 2009

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Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification

Hui Zhu, Andrew J. Bendall

published 30 Nov 2009

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Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma

Jeffrey K. Mito, Richard F. Riedel, Leslie Dodd, Guy Lahat, Alexander J. Lazar, Rebecca D. Dodd, Lars Stangenberg, William C. Eward, Francis J. Hornicek, Sam S. Yoon, Brian E. Brigman, Tyler Jacks, Dina Lev, Sayan Mukherjee, David G. Kirsch

published 30 Nov 2009

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Formation of Polyglutamine Inclusions in a Wide Range of Non-CNS Tissues in the HdhQ150 Knock-In Mouse Model of Huntington's Disease

Hilary Moffitt, Graham D. McPhail, Ben Woodman, Carl Hobbs, Gillian P. Bates

published 30 Nov 2009

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