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Mouse models

TGF-β Inhibition Restores Terminal Osteoblast Differentiation to Suppress Myeloma Growth

Kyoko Takeuchi, Masahiro Abe, Masahiro Hiasa, Asuka Oda, Hiroe Amou, Shinsuke Kido, Takeshi Harada, Osamu Tanaka, Hirokazu Miki, Shingen Nakamura, Ayako Nakano, Kumiko Kagawa, Kenichiro Yata, Shuji Ozaki, Toshio Matsumoto

published 25 Mar 2010

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Muscleblind1, but Not Dmpk or Six5, Contributes to a Complex Phenotype of Muscular and Motivational Deficits in Mouse Models of Myotonic Dystrophy

Anna Matynia, Carina Hoi Ng, Warunee Dansithong, Andy Chiang, Alcino J. Silva, Sita Reddy

published 25 Mar 2010

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C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin

John S. House, Songyun Zhu, Rakesh Ranjan, Keith Linder, Robert C. Smart

published 23 Mar 2010

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Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

Belen Tizon, Susmita Sahoo, Haung Yu, Sebastien Gauthier, Asok R. Kumar, Panaiyur Mohan, Matthew Figliola, Monika Pawlik, Anders Grubb, Yasuo Uchiyama, Urmi Bandyopadhyay, Ana Maria Cuervo, Ralph A. Nixon, Efrat Levy

published 23 Mar 2010

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Comparative Efficacy of Hemagglutinin, Nucleoprotein, and Matrix 2 Protein Gene-Based Vaccination against H5N1 Influenza in Mouse and Ferret

Srinivas S. Rao, Wing-Pui Kong, Chih-Jen Wei, Neal Van Hoeven, J. Patrick Gorres, Martha Nason, Hanne Andersen, Terrence M. Tumpey, Gary J. Nabel

published 23 Mar 2010

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Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice

Jung Min Han, Nam Hoon Kwon, Jin Young Lee, Seung Jae Jeong, Hee Jung Jung, Hyeong Rae Kim, Zihai Li, Sunghoon Kim

published 23 Mar 2010

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Cytosolic Hsp60 Is Involved in the NF-κB-Dependent Survival of Cancer Cells via IKK Regulation

Jung Nyeo Chun, Boae Choi, Kyung Wha Lee, Doo Jae Lee, Dong Hoon Kang, Joo Young Lee, In Sung Song, Hye In Kim, Sang-Hee Lee, Hyeon Soo Kim, Na Kyung Lee, Soo Young Lee, Kong-Joo Lee, Jaesang Kim, Sang Won Kang

published 23 Mar 2010

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Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1^H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking

Shinji Hadano, Asako Otomo, Ryota Kunita, Kyoko Suzuki-Utsunomiya, Akira Akatsuka, Masato Koike, Masashi Aoki, Yasuo Uchiyama, Yasuto Itoyama, Joh-E Ikeda

published 22 Mar 2010

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Comprehensive Behavioral Testing in the R6/2 Mouse Model of Huntington's Disease Shows No Benefit from CoQ10 or Minocycline

Liliana B. Menalled, Monica Patry, Natalie Ragland, Phillip A. S. Lowden, Jennifer Goodman, Jennie Minnich, Benjamin Zahasky, Larry Park, Janet Leeds, David Howland, Ethan Signer, Allan J. Tobin, Daniela Brunner

published 22 Mar 2010

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Murine Neural Stem/Progenitor Cells Protect Neurons against Ischemia by HIF-1α–Regulated VEGF Signaling

Kate M. Harms, Lu Li, Lee Anna Cunningham

published 22 Mar 2010

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Synaptic Plasticity in the Hippocampus of a APP/PS1 Mouse Model of Alzheimer's Disease Is Impaired in Old but Not Young Mice

Simon Gengler, Alison Hamilton, Christian Hölscher

published 22 Mar 2010

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Cyclotraxin-B, the First Highly Potent and Selective TrkB Inhibitor, Has Anxiolytic Properties in Mice

Maxime Cazorla, Anne Jouvenceau, Christiane Rose, Jean-Philippe Guilloux, Catherine Pilon, Alex Dranovsky, Joël Prémont

published 19 Mar 2010

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Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation

Kiran Mahajan, Domenico Coppola, Sridevi Challa, Bin Fang, Y. Ann Chen, Weiwei Zhu, Alexis S. Lopez, John Koomen, Robert W. Engelman, Charlene Rivera, Rebecca S. Muraoka-Cook, Jin Q. Cheng, Ernst Schönbrunn, Said M. Sebti, H. Shelton Earp, Nupam P. Mahajan

published 19 Mar 2010

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