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Mouse models

The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice

Hakim Ben Abdallah, Giorgia Marino, [ ... ], Claus Johansen

Piperine alleviates nonalcoholic steatohepatitis by inhibiting NF-κB-mediated hepatocyte pyroptosis

Suye Ran, Lingyu Song, [ ... ], Qi Liu

L-fucose reduces gut inflammation due to T-regulatory response in Muc2 null mice

Natalia A. Feofanova, Victoria D. Bets, Mariya A. Borisova, Ekaterina A. Litvinova

Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice

Fabrizio Grosjean, Elena M. Yubero-Serrano, [ ... ], Gary E. Striker

Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis

Liming Wang, Yuping Tang, Anne F. Buckley, Robert F. Spurney

Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia

Hildegard Nikki Hall, Hemant Bengani, [ ... ], David R. FitzPatrick

Systemic analysis shows that cold exposure modulates triglyceride accumulation and phospholipid distribution in mice

Isabella James, Raghav Jain, [ ... ], Samuel Furse

Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome

Claudia Cannavo, Karen Cleverley, [ ... ], Frances K. Wiseman

Advanced photon counting CT imaging pipeline for cardiac phenotyping of apolipoprotein E mouse models

Alex J. Allphin, Ali Mahzarnia, [ ... ], Cristian T. Badea

An oral cholera vaccine in the prevention and/or treatment of inflammatory bowel disease

Marine Meunier, Adrian Spillmann, [ ... ], Melissa Hanson

Effects of Gryllus bimaculatus and Oxya chinensis sinuosa extracts on brain damage via blood-brain barrier control and apoptosis in mice with pentylenetetrazol-induced epilepsy

Ngoc Buu Tran, Sook-Jeong Lee

Wild mouse gut microbiota limits initial tuberculosis infection in BALB/c mice

Min Xie, Chen-Yu Tsai, [ ... ], Martin Gengenbacher

Differential transcriptomic changes in the central nervous system and urinary bladders of mice infected with a coronavirus

Taylor C. Clarkson, Nao Iguchi, Alison Xiaoqiao Xie, Anna P. Malykhina

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