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Mouse models

Developmental Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia

Giuseppe Sciamanna, Annalisa Tassone, Giuseppina Martella, Georgia Mandolesi, Francesca Puglisi, Dario Cuomo, Grazia Madeo, Giulia Ponterio, David George Standaert, Paola Bonsi, Antonio Pisani

published 02 Sep 2011

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Removal of GABA_A Receptor γ2 Subunits from Parvalbumin Neurons Causes Wide-Ranging Behavioral Alterations

Elli Leppä, Anni-Maija Linden, Olga Y. Vekovischeva, Jerome D. Swinny, Ville Rantanen, Esko Toppila, Harald Höger, Werner Sieghart, Peer Wulff, William Wisden, Esa R. Korpi

published 02 Sep 2011

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Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

George M. Philips, Isaac S. Chan, Marzena Swiderska, Vanessa T. Schroder, Cynthia Guy, Gamze F. Karaca, Cynthia Moylan, Talaignair Venkatraman, Sebastian Feuerlein, Wing-Kin Syn, Youngmi Jung, Rafal P. Witek, Steve Choi, Gregory A. Michelotti, Fatima Rangwala, Elmar Merkle, Christopher Lascola, Anna Mae Diehl

published 02 Sep 2011

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Necdin Protects Embryonic Motoneurons from Programmed Cell Death

Julianne Aebischer, Rachel Sturny, David Andrieu, Anne Rieusset, Fabienne Schaller, Sandrine Geib, Cédric Raoul, Françoise Muscatelli

published 02 Sep 2011

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Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1^G93A Mouse Model of ALS and Is Harmful in Female Mice

Hannah M. Kaneb, Paul S. Sharp, Nazanin Rahmani-Kondori, Dominic J. Wells

published 01 Sep 2011

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Acute Insulin Stimulation Induces Phosphorylation of the Na-Cl Cotransporter in Cultured Distal mpkDCT Cells and Mouse Kidney

Eisei Sohara, Tatemitsu Rai, Sung-Sen Yang, Akihito Ohta, Shotaro Naito, Motoko Chiga, Naohiro Nomura, Shih-Hua Lin, Alain Vandewalle, Eriko Ohta, Sei Sasaki, Shinichi Uchida

published 31 Aug 2011

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Utility of Survival Motor Neuron ELISA for Spinal Muscular Atrophy Clinical and Preclinical Analyses

Dione T. Kobayashi, Rory J. Olson, Laurel Sly, Chad J. Swanson, Brett Chung, Nikolai Naryshkin, Jana Narasimhan, Anuradha Bhattacharyya, Michael Mullenix, Karen S. Chen

published 31 Aug 2011

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Dietary α-Eleostearic Acid Ameliorates Experimental Inflammatory Bowel Disease in Mice by Activating Peroxisome Proliferator-Activated Receptor-γ

Stephanie N. Lewis, Lera Brannan, Amir J. Guri, Pinyi Lu, Raquel Hontecillas, Josep Bassaganya-Riera, David R. Bevan

published 31 Aug 2011

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Global Analysis of Gene Expression in the Developing Brain of Gtf2ird1 Knockout Mice

Jennifer O'Leary, Lucy R. Osborne

published 31 Aug 2011

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Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease

Kaan E. Biron, Dara L. Dickstein, Rayshad Gopaul, Wilfred A. Jefferies

published 31 Aug 2011

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Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice

Wen-yi Wang, Jie Zhang, Wen-yu Wu, Jie Li, Yan-ling Ma, Wei-hai Chen, Hong Yan, Kai Wang, Wen-wei Xu, Jian-hua Shen, Yi-ping Wang

published 31 Aug 2011

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Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease

Shuhua Chen, Jun Ming Wang, Ronald W. Irwin, Jia Yao, Lifei Liu, Roberta Diaz Brinton

published 30 Aug 2011

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Diannexin Protects against Renal Ischemia Reperfusion Injury and Targets Phosphatidylserines in Ischemic Tissue

Kimberley E. Wever, Frank A. D. T. G. Wagener, Cathelijne Frielink, Otto C. Boerman, Gert J. Scheffer, Anthony Allison, Rosalinde Masereeuw, Gerard A. Rongen

published 30 Aug 2011

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